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Search Results (815)

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15 pages, 5982 KiB  
Article
Effects of Irrigation Methods on Growth and Water Productivity in Bell Pepper Cultivation in Northern South Korea
by Hwichan Yang, Yunhyeong Bae, Youngho Kim, Soonjae Hyeon, Minseong Choi, Seongho Yang, Daehyun Kim and Dongcheol Jang
Horticulturae 2024, 10(12), 1353; https://doi.org/10.3390/horticulturae10121353 - 16 Dec 2024
Viewed by 255
Abstract
Although the bell pepper (Capsicum annuum L.) is sensitive to water stress, little information is available on proper irrigation management methods for bell pepper cultivation in the northern South Korean climate. We compared the effects of different irrigation methods on crop growth [...] Read more.
Although the bell pepper (Capsicum annuum L.) is sensitive to water stress, little information is available on proper irrigation management methods for bell pepper cultivation in the northern South Korean climate. We compared the effects of different irrigation methods on crop growth and water productivity in two bell pepper varieties (Maldonado and Nagano) at different irrigation durations (ending 3 h before sunset and ending 4 h before sunset) and irrigation quantities (placing two, three, and four drippers capable of irrigating at 2 L·h−1) over approximately 280 days by performing in-depth analysis of various growth indicators. The plant height of Maldonado increased as the irrigation amount increased in all irrigation treatments of T1 and T2. In Nagano, there was no significant difference in plant height between D3 and D4. Overall, the irrigation treatments produced a higher difference in yield in Maldonado plants than in Nagano plants. WP tended to increase inversely to reduction in irrigation quantity in Groups 1 (May–June) and 4 (November–December) of both varieties, and response to irrigation stop time varied among the varieties. We inferred that the optimal irrigation method for bell pepper cultivation in northern South Korea is to supply irrigation at the D3 level and adjust the irrigation end time according to the variety and crop strength. Full article
(This article belongs to the Special Issue Advances in Sustainable Cultivation of Horticultural Crops)
14 pages, 315 KiB  
Article
Variational Information Principles to Unveil Physical Laws
by D. Bernal-Casas and J. M. Oller
Mathematics 2024, 12(24), 3941; https://doi.org/10.3390/math12243941 - 14 Dec 2024
Viewed by 319
Abstract
This article demonstrates that the application of the variation method to purely information-theoretic models can lead to the discovery of fundamental equations in physics, such as Schrödinger’s equation. Our solution, expressed in terms of information parameters rather than physical quantities, suggests a profound [...] Read more.
This article demonstrates that the application of the variation method to purely information-theoretic models can lead to the discovery of fundamental equations in physics, such as Schrödinger’s equation. Our solution, expressed in terms of information parameters rather than physical quantities, suggests a profound implication—Schrödinger’s equation can be viewed as a unique physical expression of a more profound informational formalism, inspiring new avenues of research. Full article
11 pages, 1121 KiB  
Article
Genetic Sex Determination of Free-Ranging Short-Finned Pilot Whales from Blow Samples
by Patricia Arranz, Ruth Coya, Elena Turac and Laura Miralles
Conservation 2024, 4(4), 860-870; https://doi.org/10.3390/conservation4040051 - 12 Dec 2024
Viewed by 656
Abstract
Whale blow, the vapor exhaled during respiration of cetaceans, provides valuable genetic information to monitor health status and population dynamics. However, obtaining samples of sufficient quality and quantity remains a challenge, particularly for small odontocetes. Here, we developed both field and laboratory protocols [...] Read more.
Whale blow, the vapor exhaled during respiration of cetaceans, provides valuable genetic information to monitor health status and population dynamics. However, obtaining samples of sufficient quality and quantity remains a challenge, particularly for small odontocetes. Here, we developed both field and laboratory protocols optimized for the genetic analysis of blow samples of short-finned pilot whales (Globicephala macrorhynchus). Blow collection was performed from a small research vessel at a slow speed using a hand-held carbon fiber pole equipped with a sterile Petri dish. Determination of the sex was conducted using up to five PCRs of multiplexed markers from a classical methodology (SRY + ZFX/ZFY genes) and a novel protocol (SRY + FCB17) optimized for highly degraded, fragmented and/or scarce DNA. A total of 47 blow samples of free-ranging pilot whales off the Canary Islands were collected. The presence of DNA was confirmed in 98% of the blow samples, which were further processed resulting in 32 of them with positive genetic sex determination applying the novel methodology (70%), compared to only 8 (19%) with the classical method. Results confirmed the success of sampling, DNA extraction and sex determination using multiplexed markers in blow samples of odontocetes. This protocol represents an important management tool to conduct future non-invasive health assessments of small cetaceans in the wild. Full article
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<p>(<b>A</b>) Slow-speed vessel approach for blow collection of an adult male SFPW; (<b>B</b>) decipher SLR picture of dorsal fin for photo-ID of a blow-sampled individual. Detail of the carbon-fiber pole equipped with the sterile Petri dish used to collect whale’s blow. Photo credits: Patricia Arranz (<b>A</b>) and Dacil Ridolfi (<b>B</b>), University of La Laguna, with authorization of the Spanish Ministry for the Ecological Transition and the Demographic Challenge (#AUTSPP/19/2023; #AUTSPP/33/2024).</p>
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<p>Visualization of the different sex determination methods in agarose gel. (<b>A</b>) Diagram of the different fragments ordered by size and expected results (references) with a representation of the two different methods (classical and novel). (<b>B</b>) Results of sex determination in blow samples using the classical multiplex-PCR methodology following Jayasankar et al. [<a href="#B25-conservation-04-00051" class="html-bibr">25</a>] in 2% agarose gel. (<b>C</b>) Novel FCB17 multiplex-PCR proposed methodology for blow samples and highly fragmented or degraded samples in 3% agarose gel. ML, DNA Perfect Ladder 100–1000 bp (EURx<sup>®</sup>, Gdańsk, Poland); M, Male; M*, incomplete PCR result for a male; F, Female; C-PCR Negative control (no DNA).</p>
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14 pages, 2028 KiB  
Article
The Role of Visual Information Quantity in Fine Motor Performance
by Giulia Panconi, Vincenzo Sorgente, Sara Guarducci, Riccardo Bravi and Diego Minciacchi
J. Funct. Morphol. Kinesiol. 2024, 9(4), 267; https://doi.org/10.3390/jfmk9040267 - 11 Dec 2024
Viewed by 341
Abstract
Background/Objectives: Fine motor movements are essential for daily activities, such as handwriting, and rely heavily on visual information to enhance motor complexity and minimize errors. Tracing tasks provide an ecological method for studying these movements and investigating sensorimotor processes. To date, our understanding [...] Read more.
Background/Objectives: Fine motor movements are essential for daily activities, such as handwriting, and rely heavily on visual information to enhance motor complexity and minimize errors. Tracing tasks provide an ecological method for studying these movements and investigating sensorimotor processes. To date, our understanding of the influence of different quantities of visual information on fine motor control remains incomplete. Our study examined how variations in the amount of visual feedback affect motor performance during handwriting tasks using a graphic pen tablet projecting on a monitor. Methods: Thirty-seven right-handed young adults (20 to 35 years) performed dot-to-dot triangle tracing tasks under nine experimental conditions with varying quantities of visual cues. The conditions and triangle shape rotations were randomized to avoid motor training or learning effects. Motor performance metrics, including absolute error, time of execution, speed, smoothness, and pressure, were analyzed. Results: As visual information increased, absolute error (from 6.64 mm to 2.82 mm), speed (from 99.28 mm/s to 57.19 mm/s), and smoothness (from 4.17 mm2/s6 to 0.80 mm2/s6) decreased, while time of execution increased (from 12.68 s to 20.85 s), reflecting a trade-off between accuracy and speed. Pressure remained constant across conditions (from 70.35 a.u. to 74.39). Spearman correlation analysis demonstrated a moderate to strong correlation between absolute error and time of execution across conditions. The Friedman test showed significant effects of experimental conditions on all motor performance metrics except for pressure, with Kendall’s W values indicating a moderate to strong effect size. Conclusion: These findings deepen our understanding of sensorimotor integration processes and could potentially have implications for optimizing motor skills acquisition and training and developing effective rehabilitation strategies. Full article
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<p>Experimental setup. The upper gray rectangles represent the conditions displayed to the participant. The conditions not represented between 9 points and full shape are summarized inside square brackets. Numbers ‘1’, ‘2’, ‘3’ were positioned around each vertex of the triangle to indicate the order in which the sides should be traced. Other informations are in the text. Below is the experimental setup. In the figure, a stylized depiction shows the seated subject drawing on a tablet while looking at the monitor.</p>
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<p>Boxplots representing the distribution of absolute error (<b>A</b>) and time of execution (<b>B</b>) across the experimental conditions. The dotted lines indicate the trendlines, obtained by connecting the means of each condition. (<b>C</b>) Comparison between the trendlines of absolute error (green) and time of execution (orange). The shaded areas around both trendlines represent the standard error of the mean. The values above the trendlines indicate the Spearman correlation coefficient R. The ‘*’ indicates that the Spearman correlation test is statistically significant, while ‘ns’ indicates no significant correlation.</p>
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<p>Boxplots representing the distribution of speed (<b>A</b>), smoothness (<b>B</b>), and pressure (<b>C</b>) across the experimental conditions. Each color gradation of the circles inside the boxplots corresponds to a different experimental condition. The dotted lines indicate the trendlines, obtained by connecting the means of each condition.</p>
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<p>Triangular heatmap of pairwise comparisons using Durbin–Conover post hoc analysis with Bonferroni correction (<span class="html-italic">p</span>-values = 0.0056) of absolute error (<b>A</b>), time of execution (<b>B</b>), speed (<b>C</b>), and smoothness (<b>D</b>). Dark green indicates <span class="html-italic">p</span>-values &lt; 0.001, light green indicates <span class="html-italic">p</span>-values between 0.001 and 0.0056, and yellow indicates non-significant <span class="html-italic">p</span>-values &gt; 0.0056.</p>
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21 pages, 7720 KiB  
Article
HPDH-MI: A High Payload Data Hiding Technique for Medical Images Based on AMBTC
by Chia-Chen Lin, Mostafa Mirzaei, En-Ting Chu and Chen Chih Cheng
Symmetry 2024, 16(12), 1634; https://doi.org/10.3390/sym16121634 - 10 Dec 2024
Viewed by 458
Abstract
In the realm of electronic health (eHealth) services powered by the Internet of Things (IoT), vast quantities of medical images and visualized electronic health records collected by IoT devices must be transmitted daily. Given the sensitive nature of medical information, ensuring the security [...] Read more.
In the realm of electronic health (eHealth) services powered by the Internet of Things (IoT), vast quantities of medical images and visualized electronic health records collected by IoT devices must be transmitted daily. Given the sensitive nature of medical information, ensuring the security of transmitted health data is paramount. To address this critical concern, this paper introduces a novel data hiding algorithm tailored for Absolute Moment Block Truncation Coding (AMBTC) in medical images, named HPDH-MI (High Payload Data Hiding for Medical Images). The proposed method embeds secret data into the AMBTC compression code inconspicuously to avoid detection by malicious users. It achieves this by first classifying AMBTC compressed blocks into four categories—flat, smooth, complex I, and complex II—using three predetermined thresholds. A 1-bit indicator, based on the proposed grouping strategy, facilitates efficient and effective block classification. A data embedding strategy is applied to each block type, focusing on block texture and taking into account the symmetric features of the pixels within the block. This approach achieves a balance between data hiding capacity, image quality, and embedding efficiency. Experimental evaluations highlight the superior performance of HPDH-MI. When tested on medical images from the Osirix database, the method achieves an average image quality of 31.22 dB, a payload capacity of 225,911 bits, and an embedding efficiency of 41.78%. These results demonstrate that the HPDH-MI method not only significantly increases the payload for concealing secret data in AMBTC compressed medical images but also maintains high image quality and embedding efficiency. This makes it a promising solution for secure data transmission in telemedicine, addressing the challenges of limited bandwidth while enhancing steganographic capabilities in eHealth applications. Full article
(This article belongs to the Special Issue Security and Privacy Challenges in 5G Networks)
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<p>Application scenarios of eHealth system transmission.</p>
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<p>Flowchart of the proposed HPDH-MI method. (<b>a</b>) The data embedding and (<b>b</b>) the data extraction.</p>
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<p>Flowchart of the proposed HPDH-MI method. (<b>a</b>) The data embedding and (<b>b</b>) the data extraction.</p>
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<p>The embedding step of the flat block.</p>
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<p>The embedding steps of the smooth block.</p>
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<p>Three parts of smooth block’s bitmap.</p>
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<p>The embedding steps of the complex I block.</p>
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<p>Reference matrix M.</p>
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<p>The embedding steps of the complex II block.</p>
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<p>The extraction steps of the flat block.</p>
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<p>The extraction steps of the smooth block.</p>
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<p>The extraction steps of the complex I block.</p>
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<p>The extraction step of the complex II block.</p>
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<p>Eight standard grayscale images.</p>
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<p>Six medical images.</p>
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<p>Comparison of the PSNR with the other four existing methods [<a href="#B3-symmetry-16-01634" class="html-bibr">3</a>,<a href="#B11-symmetry-16-01634" class="html-bibr">11</a>,<a href="#B21-symmetry-16-01634" class="html-bibr">21</a>,<a href="#B23-symmetry-16-01634" class="html-bibr">23</a>]. (<b>a</b>) Cerebrix (<b>b</b>) Goudurix (<b>c</b>) Manix (<b>d</b>) Phenix.</p>
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<p>Comparison of efficiency (%) with the other four methods [<a href="#B3-symmetry-16-01634" class="html-bibr">3</a>,<a href="#B11-symmetry-16-01634" class="html-bibr">11</a>,<a href="#B21-symmetry-16-01634" class="html-bibr">21</a>,<a href="#B23-symmetry-16-01634" class="html-bibr">23</a>].</p>
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16 pages, 1581 KiB  
Article
Personalized Secukinumab Treatment in Patients with Plaque Psoriasis Using Model-Informed Precision Dosing
by Karine Rodriguez-Fernandez, Javier Zarzoso-Foj, Marina Saez-Bello, Almudena Mateu-Puchades, Antonio Martorell-Calatayud, Matilde Merino-Sanjuan, Elena Gras-Colomer, Monica Climente-Marti and Victor Mangas-Sanjuan
Pharmaceutics 2024, 16(12), 1576; https://doi.org/10.3390/pharmaceutics16121576 - 10 Dec 2024
Viewed by 453
Abstract
Background/Objectives: Patient care and control of inflammatory disorders, such as psoriasis, can be improved by model-informed precision dosing (MIPD) techniques based on population pharmacokinetic/pharmacodynamic (PK/PD) models. Clinical dose selection decisions based on MIPD strategies need to take account of the uncertainty associated with [...] Read more.
Background/Objectives: Patient care and control of inflammatory disorders, such as psoriasis, can be improved by model-informed precision dosing (MIPD) techniques based on population pharmacokinetic/pharmacodynamic (PK/PD) models. Clinical dose selection decisions based on MIPD strategies need to take account of the uncertainty associated with the individual PK/PD model parameters, which is determined by the quantity of individual observational data collected in clinical practice. Methods: The aim of this study was to propose an approach for personalized dosage regimens of secukinumab (SCK) in 22 Spanish patients with plaque psoriasis, whose severity level was considered moderate to severe, taking into account the uncertainty associated with individual parameters in a population-based PK/PD model. Results: The link between SCK serum concentrations and Psoriasis Area and Severity Index (PASI) scores was explained using an indirect response model. A maximum inhibition (Imax) drug effect model was applied to limit the progression of psoriatic skin lesions within the turnover PD mechanism, which explains the changes in PASI scores during treatment. A first-order remission rate constant for psoriatic lesions (kout = 0.11 day−1) was estimated. Conclusions: According to the MIPD strategy, 50% of patients would require an optimized regimen and 14% would require an intensified dosage regimen in comparison to current clinical treatment. This research has shown its usefulness as a tool for choosing individualized SCK dosage regimens in patients with long-lasting plaque psoriasis to improve the probability of achieving satisfactory response levels. Full article
(This article belongs to the Special Issue Population Pharmacokinetics and Its Clinical Applications)
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<p>Workflow of the modeling process. PASI: Psoriasis Area and Severity Index; PD: pharmacodynamic; PK: pharmacokinetic; iPK: individual pharmacokinetic parameters; k<sub>a</sub>: absorption rate constant; CL: clearance; Q: intercompartmental transfer clearance; V<sub>2</sub>: central volume of distribution; V<sub>3</sub>: peripheral volume of distribution; iPD: individual pharmacodynamic parameters; k<sub>out</sub>: first-order reduction constant rate of psoriatic skin lesion; k<sub>outTOLt</sub>: first-order remission constant rate of tolerance; <math display="inline"><semantics> <mrow> <msub> <mrow> <mi>P</mi> <mi>A</mi> <mi>S</mi> <mi>I</mi> </mrow> <mrow> <mi>i</mi> </mrow> </msub> </mrow> </semantics></math>: estimated baseline levels of PASI response; I<sub>max</sub>: maximum inhibition drug effect model; IC<sub>50</sub>: concentration of the drug needed to inhibit 50% of the response; MIPD: model-informed precision dosing; q2w: once every 2 weeks, q4w: once every 4 weeks, q5w: once every 5 weeks, q6w: once every 6 weeks.</p>
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<p>Final PK/PD model representation. <span class="html-italic">F</span>: bioavailability; k<sub>in</sub>: zero-order evolution constant rate of psoriatic skin lesion; k<sub>inTOL</sub>: zero-order progression constant rate of tolerance; SLP: linear drug effect model.</p>
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<p>Predicted and observed PASI score (red) and SCK concentrations (blue) after the administration of SCK in patients with long-lasting psoriasis vulgaris. Individual predictions are represented by lines, and the SCK and PASI observations are represented by blue and red dots, respectively.</p>
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<p>Sankey diagram of the shifts in individual dosage regimens. SmPC: summary of product characteristics.</p>
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<p>Simulated trough level and absolute PASI score for all subjects after receiving 150 mg q4w, q5w, and q6w; and 300 mg q2w, q4w, q5w and q6w of SCK SC administration in the 20th cycle. The purple dots represent the simulated PASI score and their corresponding C<sub>trough-ss</sub>. The blue dashed box represents the C<sub>trough-ss</sub> (64.2–69.3 mg/L) that allows a PASI score ≤ 1 in 90% of patients. The red dashed line represents the PASI value of 1. C<sub>trough-ss</sub>: trough concentration at steady state.</p>
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8 pages, 4795 KiB  
Proceeding Paper
Unsupervised Domain Adaptive Transfer Learning for Urban Built-Up Area Extraction
by Feifei Peng, Shuai Yao, Yixiang Chen and Wenmei Li
Proceedings 2024, 110(1), 10; https://doi.org/10.3390/proceedings2024110010 - 3 Dec 2024
Viewed by 313
Abstract
Built-up areas are the main gathering place for human activities. The widespread availability of various satellite sensors provides a rich data source for mapping built-up areas. Deep learning can automatically learn multi-level features of targets from sample data in an end-to-end manner, overcoming [...] Read more.
Built-up areas are the main gathering place for human activities. The widespread availability of various satellite sensors provides a rich data source for mapping built-up areas. Deep learning can automatically learn multi-level features of targets from sample data in an end-to-end manner, overcoming the limitations of traditional methods based on handcrafted features. However, existing deep-learning-based methods rely on the quantity and distribution of sample data, and the trained models often exhibit limited generalization ability when faced with image data from novel scenarios. To effectively tackle this issue, this study proposes an unsupervised domain adaptive transfer learning method based on adversarial machine learning. This method aims to utilize the feature information of the source domain to train a classifier suitable for target domain feature discrimination without requiring a target domain label, and achieve built-up area extraction of different sensor images. The model comprises a feature extraction module, a label classification module, and a domain discrimination module. Through adversarial training, the feature knowledge from the source domain is transferred to the target domain, achieving feature alignment and efficient discrimination of built-up areas. The Gaofen-2 (GF-2) and Sentinel-2 datasets were employed for experimental evaluation. The results show that the proposed method, trained on the GF-2 image dataset (source domain), can be transferred unsupervised to the Sentinel-2 image dataset (target domain), demonstrating robust detection performance. Further comparative experiments have also demonstrated the superiority of our method in extracting built-up areas through transfer learning. Full article
(This article belongs to the Proceedings of The 31st International Conference on Geoinformatics)
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<p>Proposed framework.</p>
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<p>Extraction results of different methods: (<b>a</b>) The test images from left to right are Fu’an, Fuqing, Shenzhen1, and Shenzhen2; (<b>b</b>) Ground truths; (<b>c</b>) Baseline1; (<b>d</b>) Baseline2; (<b>e</b>) Baseline3; (<b>f</b>) Baseline4; (<b>g</b>) Proposed method.</p>
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<p>Sentinel-2 image and extraction results in Shenzhen City.</p>
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<p>Sentinel-2 image and extraction results in Zhuhai City.</p>
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<p>Sentinel-2 image and extraction results in Xiamen City.</p>
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14 pages, 2776 KiB  
Article
Applying the Efficiency Analysis Tree Method for Enhanced Eco-Efficiency in Municipal Solid Waste Management: A Case Study of Chilean Municipalities
by Ramon Sala-Garrido, Manuel Mocholi-Arce, Maria Molinos-Senante and Alexandros Maziotis
Clean Technol. 2024, 6(4), 1565-1578; https://doi.org/10.3390/cleantechnol6040075 - 21 Nov 2024
Viewed by 473
Abstract
Enhancing the eco-efficiency of municipal solid waste (MSW) services is pivotal for the shift toward a circular economy. Although the Data Envelopment Analysis (DEA) method is widely used, it is susceptible to overfitting, potentially distorting eco-efficiency assessments. This study applies the efficiency analysis [...] Read more.
Enhancing the eco-efficiency of municipal solid waste (MSW) services is pivotal for the shift toward a circular economy. Although the Data Envelopment Analysis (DEA) method is widely used, it is susceptible to overfitting, potentially distorting eco-efficiency assessments. This study applies the efficiency analysis tree (EAT) method, which synergizes machine learning and linear programming, offering a more reliable framework for eco-efficiency evaluation in the MSW sector. This innovative approach provides deeper insights into the optimal levels of operational costs and unsorted waste. The research encompasses a case study of 98 Chilean municipalities from 2015 to 2019, uncovering significant disparities in optimal operational expenses and unsorted waste quantities, which underscores the necessity for customized waste management approaches. The average eco-efficiency scores for 2015–2019 range between 0.561 and 0.566. This means that assessed municipalities can reduce unsorted waste by amounts ranging from 1,632,409 tons/year (2016) to 1,822,663 tons/year (2018). Potential economic savings estimated are 105,973 USD/year (2019), which represents 44% of the total MSW management costs. Additionally, the investigation into the effects of external factors on eco-efficiency furnishes nuanced perspectives that can guide policymakers and municipal authorities in developing effective, context-specific waste management strategies. Beyond refining eco-efficiency evaluations, this study contributes to more informed decision-making processes, aiding the progression toward sustainable waste management practices. Full article
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<p>Efficiency analysis tree (EAT) for estimating optimal operational costs and unsorted waste, where Id denotes the node; n(t) shows the number of observations; y<sub>1</sub> is the maximum operating costs in USD per year; and y<sub>2</sub> is the maximum level of unsorted waste in tons per year.</p>
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<p>Statistics of eco-efficiency scores in the provision of municipal solid waste services for assessed municipalities.</p>
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<p>Potential reduction of unsorted waste expressed in tons per year and percentage in relation to total municipal solid waste generated.</p>
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<p>Potential economic savings in managing MSW expressed in USD per year and percentage in relation to total operational costs.</p>
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18 pages, 2011 KiB  
Article
Demographic and Geographic Characteristics Associated with the Type of Prescription and Drug Expenditure: Real World Evidence for Greece During 2015–2021
by Georgios Mavridoglou and Nikolaos Polyzos
Healthcare 2024, 12(22), 2312; https://doi.org/10.3390/healthcare12222312 - 19 Nov 2024
Viewed by 893
Abstract
Aim: Electronic prescribing has allowed for the collection of prescription data in real time in Greece for the first time. Hence, the aim of the current study was to present the characteristics of prescriptions for the Greek population during the period from 2015 [...] Read more.
Aim: Electronic prescribing has allowed for the collection of prescription data in real time in Greece for the first time. Hence, the aim of the current study was to present the characteristics of prescriptions for the Greek population during the period from 2015 to 2021. Methods: This retrospective study was based on data extracted from the nationwide Greek electronic prescription database between January 2015 and December 2021. Descriptive statistics methods were used for the needs of the study. As the basic figures examined depend on the size of the population, in order for the results to be comparable, we estimated the corresponding measures per inhabitant, using population data from the Greek Statistical Authority. Appropriate indicators for the comparison of consumption and expenditure over time were estimated. A study of the trend was also carried out using time series and linear regression models. In order to facilitate the design and implementation of specialized policies, it is useful to identify the drug categories with the highest consumption and expenditure, as well as the geographical areas that present similar characteristics. For the first, ABC analysis was used, which helps to identify the most popular categories of drugs, while for the second, cluster analysis was carried out. Agglomerative clustering was used to divide the regions into similar groups. This hierarchical clustering algorithm classifies the population into several clusters, with areas in the same cluster being more similar, and areas in different clusters being dissimilar. The Ward linkage method with Euclidean distance was used. Results: The analysis of prescription drug consumption and expenditure from 2015 to 2021 revealed significant fluctuations and trends across various drug categories, age groups, and geographical areas. Notably, the quantity of prescriptions increased by 20% since 2015, while expenditure surged by over 30%, with significant spikes following the end of the MoU in 2019 and the onset of the pandemic in 2020. In terms of expenditure, antineoplastic and immunomodulation agents (category L) held the largest share, driven by the introduction of new, costly drugs. The expenditure per inhabitant revealed gender and age disparities, with older populations, particularly women, incurring higher costs. Geographically, drug expenditure, and consumption varied significantly, with distinct regional clusters identified. These clusters, while showing some overlap in consumption and expenditure patterns, also highlighted unique regional characteristics. Conclusions: The insights into prescription drug consumption and expenditure trends offer a valuable basis for developing targeted interventions aimed at optimizing healthcare resource allocation. Moreover, the findings underscore the importance of addressing regional and demographic disparities in pharmaceutical use, thereby contributing to more equitable and cost-effective healthcare strategies. More specifically, the age distribution of prescriptions shows the increase in younger ages, which, as a result, anticipates the overall increase in prescriptions. The knowledge of the most convex categories of medicine, as well as the percentages of the use of generic drugs, shows where interventions should be made, with financial incentives and information through new information channels. The geographic disparities recorded should lead to policies that help the residents of hard-to-reach areas to access prescriptions. In addition, the present study provides a strategic framework for policymakers and healthcare managers to guide future studies and inform decision-making processes. Full article
(This article belongs to the Special Issue Efficiency, Innovation, and Sustainability in Healthcare Systems)
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<p>Linear trend analysis, (<b>a</b>) volume; (<b>b</b>) expenditure.</p>
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<p>ABC analysis; (<b>a</b>) for quantity and (<b>b</b>) expenditure by ATC-1 categories, 2015–2021. (A: alimentary tract and metabolism; B: blood and blood-forming organs; C: cardiovascular system; D: dermatology; G: genito-urinary system and sexual hormones; H: systemic hormonal preparations; J: anti-infectives for systemic use; L: antineoplastic and immunomodulating; M: musculo-skeletal system; N: nervous system; P: antiparasitic products; R: respiratory system; S: sensory organs; V: various).</p>
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<p>Ratio (expenditure/quantity) per year and ATC-1 category (A: alimentary tract and metabolism; B: blood and blood-forming organs; C: cardiovascular system; D: dermatology; G: genito-urinary system and sexual hormones; H: systemic hormonal preparations; J: anti-infectives for systemic use; L: antineoplastic and immunomodulating; M: musculo-skeletal system; N: nervous system; P: antiparasitic products; R: respiratory system; S: sensory organs; V: various).</p>
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<p>Consumption and expenditure per capita by sex and age group, as a per cent of mean, 2015–2021.</p>
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<p>Cluster analysis. Dendrograms of regions by (<b>a</b>) quantities and (<b>b</b>) values.</p>
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28 pages, 53103 KiB  
Article
Interdisciplinary Research for the Delimitation of Catchment Areas of Large Deep Karstic Aquifers: Origin of the Thermal Springs of Alhama de Aragón and Jaraba (Spain)
by Joaquín Sanz De Ojeda, Francisco Javier Elorza and Eugenio Sanz
Water 2024, 16(22), 3303; https://doi.org/10.3390/w16223303 - 17 Nov 2024
Cited by 1 | Viewed by 651
Abstract
The integration of different sources of geological and hydrogeological information and the application of interdisciplinary methods have informed the origin of the thermal springs of Alhama de Aragón and Jaraba, as well as other associated semi thermal springs (1200 L/s of combined flow, [...] Read more.
The integration of different sources of geological and hydrogeological information and the application of interdisciplinary methods have informed the origin of the thermal springs of Alhama de Aragón and Jaraba, as well as other associated semi thermal springs (1200 L/s of combined flow, 711 L/s at over 30 °C), which is the main objective of this article. These springs come mainly from the autogenous recharge that occurs in the Cretaceous calcareous outcrops that border the Almazán Basin to the north, both in the Ebro Basin (Jalón Valley) and in the Duero Basin. The aquifer, shaped by upper Cretaceous limestones under the Palaeogene and Neogene rocks of the Almazán Basin, has extensive depths of more than 4000 m in the NE sector. This hydrostratigraphic unit has been affected by a generalized pre-Paleogene karstification that provides the main porosity to the aquifer. The underground flow moves in a NW–SE direction, crossing the Duero–Ebro divide, favoured by the topographic difference in elevation between the two basins. The regional flow is coherent with the progressive increase in temperature, infiltrating recharge water age (about 20–25 years in the semi-thermal springs, and more than 60 years in the Alhama and Jaraba springs), mineralization, and flow of the springs through which the system discharges. This issue is key to being able to design any sustainable conservation strategy in terms of quantity and quality of resources within the recharge area of the most important thermal springs in Spain. The Jaraba and Alhama de Aragón hot springs share the same or similar temperature, chemical composition, and geological contact of the spring. Their tritium isotopic composition and its evolution over time are practically the same. Their isotopic composition in D and 18O is also very similar. Both springs share the same recharge zone of similar altitude and constitute the end of flow tubes of similar length and flow rate. Full article
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<p>Location map of the study area. (<b>B</b>) Areas of maximum accumulation of Palaeogene and Neogene sediments in the Duero Basin (according to [<a href="#B14-water-16-03303" class="html-bibr">14</a>]) and location of the Almazán Basin (CA), Aragonese Branch (RA), and Castellana Branch (RC) of the Cordillera Iberian. (<b>A</b>) Geological scheme of the Almazán Basin (Modified from [<a href="#B15-water-16-03303" class="html-bibr">15</a>,<a href="#B16-water-16-03303" class="html-bibr">16</a>]), and location of the main groups of springs: (1) thermal, more than 30 °C, (2) semithermal, between 20 and 30 °C and (3) those with temperatures above between 4 °C and 8 °C above the average temperature of the sources in the area, which is about 11 °C (4) Watershed between the Ebro Basin and the Duero and Tajo basins; (5) Iberian Massif; (6) Pyrenees; (7) Betic Cordillera; (8) Palaeogene and Neogene Basin; (9) Iberian Range and Catalan-Coastal Range.</p>
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<p>Geological diagram of the study area with indication of the extension of the Jurassic below the Cenozoic, detail of the Paleogene stratigraphy and location of the karstification processes in the Cretaceous. 1. Precambrian and Paleozoic: quartzites and shales. 2. Lower and Middle Triassic: sandstones of the Buntsandstein facies and dolomites and marls of the Muchelcalk facies. 3. Upper Triassic: clays and gypsum of the Keuper facies. 4. Lower Jurassic: Dolomites. 5. Middle and Upper Jurassic: limestones and marls. 6. Cretaceous: Utrillas facies sands below. Upper limestones and marls. 7. Palaeogene of the Northern Zone (adapted from Huerta 2007). (7.1. Ocino Fm., 7.2. Almazul Fm., 7.3. Gomara Fm., 7.4. Gomara Fm., 7.5. Peroniel Fm., 7.6. Fm., 7.7. Bordalba Fm., 7.8. Deza Fm., 7.9. Valdehurtado Fm., 7.10. El Raido, 7.11. Alparrache Fm.). 8. Neogene: shales, siltstones, conglomerates. 9. Jurassic boundary below the Cenozoic. 10. Traces of pre-Palaeogene karstification at the Cretaceous-Palaeogene and Neogene rocks contact (according to [<a href="#B19-water-16-03303" class="html-bibr">19</a>]). 11. Traces of karstification due to the circulation of thermal and semi-thermal waters at the Cretaceous-Palaeogene and Neogene rocks contact (according to [<a href="#B6-water-16-03303" class="html-bibr">6</a>]). 12. Water divide between the Duero–Ebro. 13. Water divide between the Ebro-Tajo. 14. Overview of signs of karstification at the Cretaceous-Palaeogene and Neogene rocks contact.</p>
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<p><b>Hydrogeological diagram of the study area. Geological features description:</b> 1. Precambrian and Palaeozoic: quartzites and shales. 2. Lower and Middle Triassic: sandstones of the Buntsandstein facies and dolomites and marls of the Muchelcalk facies. 3. Upper Triassic: clays and gypsum of the Keuper facies. 4. Lower Jurassic: Carniolas (dolomites with small cavities) and dolomites. 5. Middle and Upper Jurassic: limestones and marls. 6. Cretaceous: Utrillas facies sands below. Upper limestones and marls. 7. Paleogene of the Northern Zone (adapted from [<a href="#B16-water-16-03303" class="html-bibr">16</a>]). 8. Neogene: shales, siltstones, conglomerate. 9. Jurassic boundary under the Cenozoic. <b>Hydrographical and hydrogeological features description</b>: 10. Water divide between the Duero–Ebro. 11. Water divide between the Ebro–Tajo. 12. Group of thermal springs (12.1. Jaraba. 12.2. Alhama de Aragón). 13. Group of semi-thermal springs (13.1. Embid de Ariza. 13.2. San Roquillo. 13.3. Deza. 13.4. Almazul). 14. Important cold springs in the Sierra del Solorio (14.1. Mochales. 14.2. Iruecha. 14.3. Chaorna. 14.4. Sagides. 14.5. Urex. 14.6. Layna. 14.7. Ambrona. 14.8. Esteras de Medinaceli or source of the river Jalón). 15. Poljes of the Rituerto river. 16. Flow lines in the Sierra del Solorio. 17. Sinkholes in the Mesa river. 18. Ground water contour and surface flow lines in the Tertiary of the Almazan Basin. <b>Detail</b> (<b>A</b>). Detailed location of springs in the Almazul area associated with the Palaeogene and Cretaceous (geological base taken from [<a href="#B16-water-16-03303" class="html-bibr">16</a>]). <b>Detail</b> (<b>B</b>). Detail of the location of the group of springs in the Cretaceous calcareous aquifer in Deza and San Roquillo, differentiating between deep flow (orange) and shallow flow (blue) (geological base taken from [<a href="#B16-water-16-03303" class="html-bibr">16</a>]). <b>Detail</b> (<b>C</b>). Detail of the situation of the group of thermal springs (red) and boreholes of the Cretaceous–calcareous and Palaeogene and Neogene aquifer (T) in Alhama de Aragón. <b>Detail</b> (<b>D</b>). Detail of the situation of the group of thermal springs (red), cold springs (blue), and boreholes of the Cretaceous–calcareous and Palaeogene and Neogene aquifer in Jaraba area.</p>
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<p>Schematic hydrogeological cross-section along the bottom of the Almazán Basin showing the hydrogeological divide established in the mathematical model for the Cretaceous-Thermal aquifer. 1. Palaeogene and Neogene sediments of the Almazán Basin. 2. Edges of the Almazán Basin (mainly carbonate aquifer). 3. Topographic contour lines. 4. Depth of the top of the Cretaceous-thermal aquifer. 5. Water table. 6. Duero–Ebro surface divide. 7. Duero–Ebro hydrogeological divide, verified at the edges and assumed in the interior of the basin. 8. Duero–Ebro hydrogeological divide, maximum assumed position. 9. Springs. 10. Flow lines. 11. Hydrogeological cut (the power of the Cretaceous-thermal calcareous aquifer is exaggerated).</p>
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<p>Comparison of tritium values of groundwater samples with those of annual precipitation in Zaragoza and Madrid, belonging to the REVIP period 1953–2018 in semi-logarithmic scale. (A. Precipitation in Madrid. B. Precipitation in Zaragoza. C. Deza springs. D. San Roquillo springs. E. Springs of Alhama de Aragón. F. Jaraba spring).</p>
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<p>Result of piezometric levels after the calibration of the numerical model [<a href="#B2-water-16-03303" class="html-bibr">2</a>].</p>
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<p>Evolution of the tritium content of precipitation in Madrid and in the springs of the Alhama de Aragón thermal aquifer (A. Precipitation in Madrid. B. Precipitation in Zaragoza. C. Deza springs. D. San Roquillo springs. E. Embid de Ariza. F. Springs of Alhama de Aragón. G. Jaraba spring (own data and from [<a href="#B8-water-16-03303" class="html-bibr">8</a>,<a href="#B11-water-16-03303" class="html-bibr">11</a>,<a href="#B47-water-16-03303" class="html-bibr">47</a>,<a href="#B48-water-16-03303" class="html-bibr">48</a>]).</p>
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<p>Piper diagram of the chemical composition of the waters of the springs of the thermal system. (A. Alhama de Aragón springs. B. Jaraba springs. C. Embid de Ariza spring. D. San Roquillo springs. E. Deza springs F. Cold springs). (own data and from [<a href="#B8-water-16-03303" class="html-bibr">8</a>,<a href="#B11-water-16-03303" class="html-bibr">11</a>,<a href="#B47-water-16-03303" class="html-bibr">47</a>]).</p>
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<p>(<b>Left</b>): Relationship between <sup>18</sup>O values and their chloride content in the springs (in mg/L) of the Alhama de Aragón thermal aquifer. (<b>Right</b>): Increase in mineralisation of the springs (TDI) according to the regional flow.</p>
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17 pages, 1018 KiB  
Article
Fault Diagnosis Method for Converter Stations Based on Fault Area Identification and Evidence Information Fusion
by Shuzheng Wang, Xiaoqi Wang, Xuchao Ren, Ye Wang, Sudi Xu, Yaming Ge and Jiahao He
Sensors 2024, 24(22), 7321; https://doi.org/10.3390/s24227321 - 16 Nov 2024
Viewed by 502
Abstract
DC converter stations have a high voltage level, a long transmission distance, and complex internal equipment, and contain power electronic devices, which seriously endanger the stable operation of the system itself and the active distribution network at the receiving end when faults occur. [...] Read more.
DC converter stations have a high voltage level, a long transmission distance, and complex internal equipment, and contain power electronic devices, which seriously endanger the stable operation of the system itself and the active distribution network at the receiving end when faults occur. Accurate fault analysis and diagnosis are critical to the safe and stable operation of power systems. Traditional fault diagnosis methods often rely on a single source of information, leading to issues such as insufficient information utilization and incomplete diagnostic scope when applied to DC transmission systems. To address these problems, a fault diagnosis method for converter stations based on preliminary identification of the fault range and the fusion of evidence information of the switch signal and electrical quantity is proposed. First, the preprocessing of converter station sequential event recording (SER) events and a statistical analysis of event characteristics are completed to initially determine the range of the fault.Then, a fuzzy Petri net model and a BP neural network model are constructed on the basis of the fault data from a real-time digital simulation system (RTDS), and the corresponding evidence information of the switch signal and electrical quantity are obtained via iterative inference and deep learning methods. Finally, on the basis of D-S evidence theory, a comprehensive diagnosis result is obtained by fusing the switch and electric evidence information. Taking the fault data of a DC converter station as an example, the proposed method is analyzed and compared with the traditional method, which is based on single information. The results show that the proposed method can reliably and accurately identify fault points in the protected area of the converter station. Full article
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<p>Converter station fault point diagram.</p>
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<p>Converter station fault diagnosis method.</p>
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<p>Analysis results of SER events.</p>
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<p>Petri net construction process.</p>
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<p>Fuzzy Petri net model for switch signal diagnosis of converter station.</p>
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<p>BP neural network structure diagram.</p>
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<p>Results of 8-layer wavelet decomposition of direct current.</p>
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<p>Wavelet energy distribution condition.</p>
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<p>Diagram of RTDS simulation model of DC field structure.</p>
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16 pages, 3431 KiB  
Article
Sample Inflation Interpolation for Consistency Regularization in Remote Sensing Change Detection
by Zuo Jiang, Haobo Chen and Yi Tang
Mathematics 2024, 12(22), 3577; https://doi.org/10.3390/math12223577 - 15 Nov 2024
Viewed by 434
Abstract
Semi-supervised learning has gained significant attention in the field of remote sensing due to its ability to effectively leverage both a limited number of labeled samples and a large quantity of unlabeled data. An effective semi-supervised learning approach utilizes unlabeled samples to enforce [...] Read more.
Semi-supervised learning has gained significant attention in the field of remote sensing due to its ability to effectively leverage both a limited number of labeled samples and a large quantity of unlabeled data. An effective semi-supervised learning approach utilizes unlabeled samples to enforce prediction consistency under minor perturbations, thus reducing the model’s sensitivity to noise and suppressing false positives in change-detection tasks. This principle underlies consistency regularization-based methods. However, while these methods enhance noise robustness, they also risk overlooking subtle but meaningful changes, leading to information loss and missed detections. To address this issue, we introduce a simple yet efficient method called Sample Inflation Interpolation (SII). This method leverages labeled sample pairs to mitigate the information loss caused by consistency regularization. Specifically, we propose a novel data augmentation strategy that generates additional change samples by combining existing supervised change samples with calculated proportions of change areas. This approach increases both the quantity and diversity of change samples in the training set, effectively compensating for potential information loss and reducing missed detections. Furthermore, to prevent overfitting, small perturbations are applied to the generated sample pairs and their labels. Experiments conducted on two public change detection (CD) datasets validate the effectiveness of our proposed method. Remarkably, even with only 5% of labeled training data, our method achieves performance levels that closely approach those of fully supervised learning models. Full article
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<p>The overall network framework.</p>
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<p>The overall framework of the proposed interpolation method applied to semi-supervised change detection.</p>
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<p>(<b>a</b>) image before the change, (<b>b</b>) image after the change, (<b>c</b>) RCR, (<b>d</b>) ECPS, (<b>e</b>) ours, (<b>f</b>) ground truth.</p>
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<p>(<b>a</b>) image before the change, (<b>b</b>) image after the change, (<b>c</b>) RCR, (<b>d</b>) ECPS, (<b>e</b>) ours, (<b>f</b>) ground truth.</p>
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30 pages, 11342 KiB  
Article
Secure Dual Network for Reversible Facial Image Anonymization Through the Latent Space Manipulation
by Yi-Lun Pan, Jun-Cheng Chen and Ja-Ling Wu
Electronics 2024, 13(22), 4398; https://doi.org/10.3390/electronics13224398 - 9 Nov 2024
Viewed by 508
Abstract
We develop a method to automatically and stably anonymize and de-anonymize face images with encoder-decoder networks and provide a robust and secure solution for identity protection. Our fundamental framework is a Neural Network (NN)-based encoder-decoder pair with a dual inferencing mechanism. We denote [...] Read more.
We develop a method to automatically and stably anonymize and de-anonymize face images with encoder-decoder networks and provide a robust and secure solution for identity protection. Our fundamental framework is a Neural Network (NN)-based encoder-decoder pair with a dual inferencing mechanism. We denote it as the Secure Dual Network (SDN), which can simultaneously achieve multi-attribute face de-identification and re-identification without any pre-trained/auxiliary model. In more detail, the SDN can take responsibility for successfully anonymizing the face images while generating surrogate faces, satisfying the user-defined specific conditions. Meanwhile, SDN can also execute the de-anonymization procedure and visually indistinguishably reconstruct the original ones if re-identification is required. Designing and implementing the loss functions based on information theory (IT) is one of the essential parts of our work. With the aid of the well-known IT-related quantity, Mutual Information, we successfully explained the physical meaning of our trained models. Extensive experiments justify that with pre-defined multi-attribute identity features, SDN generates user-preferred and diverse appearance anonymized faces for successfully defending against attacks from hackers and, therefore, achieves the goal of privacy protection. Moreover, it can reconstruct the original image nearly perfectly if re-identification is necessary. Full article
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<p>The schematic diagram of the proposed SDN for re-ID.</p>
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<p>SDN’s systematic structure looked at from the viewpoints of subnetworks and functional modules.</p>
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<p>The detailed structures and hyperparameters of each layer within the SDN’s subnetworks are depicted in <a href="#electronics-13-04398-f002" class="html-fig">Figure 2</a>.</p>
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<p>The conceptual schematic diagram of the operational logic and the information flows of the proposed Dual Inference Process.</p>
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<p>The comparison of the anonymization process’s quantitative evolution results between the SDN and benchmarked works regarding ID-distance concerning various testing datasets [<a href="#B15-electronics-13-04398" class="html-bibr">15</a>,<a href="#B21-electronics-13-04398" class="html-bibr">21</a>,<a href="#B22-electronics-13-04398" class="html-bibr">22</a>,<a href="#B38-electronics-13-04398" class="html-bibr">38</a>,<a href="#B39-electronics-13-04398" class="html-bibr">39</a>].</p>
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<p>The comparison of the anonymization process’s quantitative evolution results between the SDN and benchmarked works regarding SPR concerning various testing datasets [<a href="#B15-electronics-13-04398" class="html-bibr">15</a>,<a href="#B21-electronics-13-04398" class="html-bibr">21</a>,<a href="#B22-electronics-13-04398" class="html-bibr">22</a>,<a href="#B38-electronics-13-04398" class="html-bibr">38</a>,<a href="#B39-electronics-13-04398" class="html-bibr">39</a>].</p>
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<p>The SDN generated surrogate faces’ snapshots using the style-related attribute Hair color and the password as the evaluated multi-attribute combinations.</p>
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<p>The visual comparison of polluted situations in the synthesized images between competing systems, including CIAGAN [<a href="#B43-electronics-13-04398" class="html-bibr">43</a>], MfM [<a href="#B25-electronics-13-04398" class="html-bibr">25</a>], Cao et al. [<a href="#B44-electronics-13-04398" class="html-bibr">44</a>], and our SDN.</p>
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<p>The successful de-ID/re-ID Rates.</p>
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<p>The above snapshots examine the impacts of 1-bit difference passwords on a given anonymized image with varying degrees of smiling attributes, which “a<sub>1</sub>–a<sub>6</sub>” are the abbreviations for “anonymized image 1–anonymized image 6”.</p>
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<p>Block diagram of the proposed Latent Space Manipulation Module and how it is used to find the shifting guidance for a target latent space manipulation.</p>
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<p>Block diagram of the proposed Latent Space Manipulation Module and how it is used to complete the desired manipulation by adding the shifting guidance in the latent space.</p>
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<p>The snapshots of the SDN manipulated results concerning varying degrees of style-related attributes (upper: Smiling, middle: Mustache, and bottom: Mouth Open).</p>
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<p>The snapshots of the SDN manipulated results concerning varying degrees of the identity-face-related attributes, and we take gender as a testing target.</p>
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<p>Using the same input image, the visual comparison of polluted situations in the synthesized images among competing systems, including CIAGAN, MfM, and SDN.</p>
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<p>Total time consumption across three different datasets: (<b>a</b>) FaceScrub [<a href="#B4-electronics-13-04398" class="html-bibr">4</a>], (<b>b</b>) CASIA [<a href="#B5-electronics-13-04398" class="html-bibr">5</a>], and (<b>c</b>) CelebA-HQ [<a href="#B6-electronics-13-04398" class="html-bibr">6</a>].</p>
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23 pages, 4094 KiB  
Article
Assessment of Water Service Levels and User Satisfaction for Domestic Water Use in Emina-Boadi-Kumasi to Achieve the Sustainable Development of Urban Water Supply Systems in Ghana
by Emmanuel Padmore Mantey, Rameshwar S. Kanwar and Eugene Appiah-Effah
Water 2024, 16(22), 3193; https://doi.org/10.3390/w16223193 - 7 Nov 2024
Viewed by 1184
Abstract
Access to reliable water supply is critical for sustainable development and public health, yet many peri-urban and rural communities in the developing world face challenges such as poor maintenance, faulty infrastructure, and inadequate governance of water services, hindering the UN’s Sustainable Development Goals [...] Read more.
Access to reliable water supply is critical for sustainable development and public health, yet many peri-urban and rural communities in the developing world face challenges such as poor maintenance, faulty infrastructure, and inadequate governance of water services, hindering the UN’s Sustainable Development Goals (SDG). In Emina-Boadi, a small town in Kumasi, Ghana, residents increasingly rely on boreholes due to substandard service from the Ghana Water Company Limited (GWCL). This shift highlights concerns about water reliability, quality, and affordability, impacting public health and hindering progress toward SDG 6. This case study assesses water service levels using key performance indicators (KPIs) such as quantity, quality, affordability, accessibility, and reliability, focusing on sources like boreholes, hand pumps, piped water, hand-dug wells, rainwater, and surface waters. The study aims to delineate the roles of different water providers, understand community dynamics, and evaluate contributions to rural development and SDG 6 through stakeholder interviews and questionnaires. By leveraging the WASHCost framework, which aims to improve planning methods and the provision of water and sanitation services by addressing the lack of cost information in rural and peri-urban areas, and the Joint Monitoring Programme (JMP) framework, which monitors progress toward global targets related to water, sanitation, and hygiene, the study categorizes indicators and draws connections among them. The findings reveal a significant preference for borehole services, with 87% usage and an 83% reliability rate compared to 13% for GWCL. Daily water consumption averages 60.75 L per person, with on-premises access improving water collection efficiency to 7 min. Dissatisfaction with GWCL services highlights the need for improved delivery aligned with community needs and SDG targets. Adopting sustainable management practices, enhancing infrastructure, and improving governance are crucial for ensuring safe and affordable water access for all residents of Emina-Boadi and similar communities. Full article
(This article belongs to the Section Water Resources Management, Policy and Governance)
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<p>Map showing study communities and district boundaries in Kumasi, Ghana. The yellow dots highlight the locations of the households where the questionnaires were administered.</p>
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<p>Showing the proportion of each gender as well as their distribution throughout the age group.</p>
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<p>A bar chart showing the occupation distribution.</p>
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<p>(<b>a</b>) A picture of a household mechanized borehole connected to a hand pipe outside the household premises for public use at a fee, (<b>b</b>) A Picture of a public standpipe connected to a storage tank with water supplied by GWCL, (<b>c</b>–<b>e</b>) A picture showing a borehole operated manually by a hand pump; the user either pushes the hand pump up or down or spins the hand-cranked wheel, to draw water from a borehole. Source: All pictures were taken during the study except for picture (<b>d</b>,<b>e</b>) credofunding (<a href="http://www.credofundingwater.com" target="_blank">www.credofundingwater.com</a>).</p>
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<p>Chart showing the distribution of the level of satisfaction with respect to the cost of water.</p>
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<p>Relationship between water availability and level of satisfaction.</p>
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16 pages, 21457 KiB  
Article
Virtual Tumor Mapping: A New Standard for Surgeon–Pathologist Collaboration in Treating Oral Squamous Cell Carcinoma
by Adam Michcik, Maksym Jopek, Rafał Pęksa, Piotr Choma, Łukasz Garbacewicz, Adam Polcyn, Tomasz Wach, Maciej Sikora and Barbara Drogoszewska
Cancers 2024, 16(22), 3761; https://doi.org/10.3390/cancers16223761 - 7 Nov 2024
Viewed by 684
Abstract
Background: The histopathological assessment is critical in the comprehensive treatment process for patients diagnosed with oral squamous cell carcinoma (OSCC). A detailed and precise specimen characterization is essential to facilitate effective surgeon–pathologist communication. Methods: In response to this need, a user-friendly virtual communication [...] Read more.
Background: The histopathological assessment is critical in the comprehensive treatment process for patients diagnosed with oral squamous cell carcinoma (OSCC). A detailed and precise specimen characterization is essential to facilitate effective surgeon–pathologist communication. Methods: In response to this need, a user-friendly virtual communication protocol utilizing a 3D scanner has been developed. This study involved 50 patients with OSCC, whose resected tumors were directly scanned in the operating room and subsequently annotated and characterized using available software. Results: The direct application of annotations and descriptions onto the virtual tumor specimens significantly enhanced the quantity and accuracy of information conveyed to the pathologist. Conclusions: The proposed solution’s repeatability and standardized approach make integration into routine clinical practice feasible, thereby establishing a potential new standard in the field. Full article
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<p>Photo of the scanner and the turntable with the constructed stand.</p>
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<p>Tongue OSCC. The material provides a comprehensive view of the tumor on all sides, highlighting the precision of the specimens obtained through the 3D scanning technique before and after undergoing formalin fixation. Green background—photos of the tumor after excision and after formalin fixation. Black background—images of tumor scans after excision and after formalin fixation.</p>
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<p>Orbital and maxilla tumor. The image on the left side is of the tumor and the stand before scanning. The image on the right is of the tumor, created with a 3D scanner.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Comprehensive instruction for the virtual annotation, mapping, and measurements of the tumor.</p>
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<p>Simplified 3D image annotation and data exchange process.</p>
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<p>Tongue tumor mapping scheme. The virtual image facilitates the comprehensive evaluation of all tumor surfaces. Flat-labeled margins and frozen section analysis (FSA) sampling locations are visible. The figures demonstrate the mapping capabilities directly on the surface of a virtual tumor. In the course of a virtual tumor assessment, it is feasible to temporarily deactivate specific determinations. This action significantly increases the clarity of the image.</p>
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