Why is everybody looking down on it just because of the excessive gross out humour? There's more to this show than fart jokes.
Speaking on behalf of a fellow user on Tumblr, this show has an Indian protagonist, but really unlike Indian stereotypes you see on other shows; Sanjay is your average preteen who has a pet he loves, and with a fetish for junk food and/or video games.
Second, there are episodes which zoom in on his relationship with Craig (e.g. Chill Bill, Cuddle Buddy). It's what some best friends go through too. They do face adversities that endanger their brotherhood but they always conquer it in the end. Even the episodes that don't focus on such an issue do have their moments (e.g. Too Tuff to Watch, Hot Sauce Boss, Street Dogg).
P.s. this show has not 1, not 2, but 3 creators - so appreciate the effort that goes into all 3 of them trying to agree on the same ideas.
On the minus side the animation is terrible and the art style even ripped of Regular Show.