Marketed as the first film to skip its own sequel, ThanksKilling 3 follows ThanksKilling. As of 2023, there is no ThanksKilling 2.
When Turkie attaches a chainsaw to his arm he looks at the camera and says "gravy" which is an obvious reference to Ash in the Evil Dead series.
Funded through a successful Kickstarter campaign, where over $100,000 was raised. As of 2012, ThanksKilling 3 was the highest funded horror film on Kickstarter.
The original ThanksKilling was shot in 11 days. ThanksKilling 3 took over 50 days to shoot.
The graffiti covered alleyway where Uncle Donny and Yomi first meet is known as "Art Alley" in Rapid City, South Dakota.