Desi and Cata discover the corpse of a woman in the mansion they just cleaned up. After running away from some Russian hitmen, they realized that they had stolen a bag of money by mistake.
Desi and Cata try to give the Russians their money back, but they want something more: their heads. Desperate, they ask Irene, the cop handling the case and Desi's ex-girlfriend, for help.
When Irene can't help the girls due to her relationship with Desi, Cata decides to return to Mexico with Ubaldo. But the police has found her trail and leaving the country becomes impossible.
The girls interrogate Eduardo Roselló, but everything goes off the rails when the cops discover Irene is helping the girls and the Russians catch up to Desi and Cata.
With Irene arrested, and after losing the Russians again, the girls and Ubaldo hide in Dakota, a street club. There, they discover something that changes everything.
Together again, Desi, Cata and Irene have to prove that Eduardo Roselló killed his sister. But Eduardo has his own plans to blackmail Néstor and have him take the blame.
Néstor is now the main suspect, and Desi and Cata turn to Eduardo to prove it. Irene receives an ultimatum from her boss: if she doesn't capture the girls, she'll be fired from the police.
