The Lockport, IL Metro train station is used as a stand-in for Carbondale, IL's Amtrak station.
Kate's address is given as 4569 N. Baltimore Rd, Chicago, IL 60640 (on the letter to her ex boyfriend), however, the building she enters is actually 4623 N. Western Ave, Chicago, IL 60625, and is above Spyners Pub. The interiors may have been shot elsewhere.