The German version has been elaborately dubbed, using the German film voice actors for Carrie-Anne Moss, Hugo Weaving, Julia Roberts, Kevin Spacey, Nick Nolte, Uma Thurman, Gene Hackman, among others. "Alex D" is voiced by Kiefer Sutherland's German voice. These familiar voices greatly enhance the "movie" feeling.
Many devoted fans of the original Deus Ex (2000) were unhappy with some of the "streamlining" done to Invisible War, in order to make the game more accessible to casual gamers. Despite low sales on the PC, the high success of the console version ensured that the game met sales expectations.
A few of the characters in this game are clones of characters in the original Deus Ex (2000). While not directly stated, it is believed that the "Voice Of Project Director" is the clone of Walton Simons.
A joke amongst fans of Deus Ex is that the franchise is consistent when it comes to bad installments always following good installments. This is the case with Invisible War and Deus Ex: The Fall (2013)
Many fans criticized the game for it's universal ammunition system as well as combining of the augmentation and skill branches.