Karen Sisco (Carla Gugino) is a US Marshal in Miami. Her father Marshall Sisco (Robert Forster) is the only one she unequivocally trusts. Amos Andrews (Bill Duke) is her boss.
Based on the character portrayed by Jennifer Lopez in Elmore Leonard's Out of Sight, Karen Sisco is a smart, sexy, and tough character. Carla Gugino plays her with gusto. It never really took off and lasted only 7 episodes with 3 unaired remaining. I think there were two main problems.
The first is they shot this is L.A. If they could do it in Miami, it would add so much more local flavor. There is a difference and the audience can feel it. The second is the need for edginess. Seeing the successful 'Justified' (another Elmore Leonard adaptation), it seems obvious that Karen Sisco just doesn't have the grittiness in both style and substance. It just isn't Elmore Leonard enough.
