Steve Martin and Scott Caan did not get along during filming because of Caan's reckless behavior toward a stuntperson in a scene in which his character smashes a beer bottle over the head of a man in a bar.
This is the second time Steve Martin plays a dentist, the first being his role in Little Shop of Horrors (1986) as Orin Scrivello, a character far more "disturbed" than Frank Sangster.
Steve Martin played a dentist who gets high on nitrous oxide in Little Shop of Horrors (1986). That same year, Laura Dern appeared in Blue Velvet (1986), in which Dennis Hopper's villainous character breathes an unidentified inhalant.