This show is a unique and highly enjoyable experience. His interviewing style is not only hilarious to watch, but very effective at getting people to expose their most blunt and inner secrets. This means that each episode is not only a learning experience but laugh out loud funny.
This also often results in some pretty intense scenes where people reflect on their often sad lives. At this point they either get mad at him, dismiss him, or take it on board. Usually they will simply dismiss or get mad which can make the show a little depressing at points. I would say this makes the humour more appealing to fans of shows like The Office and other British comedies, but also funny for and American audience because of Louis naive character.