The rattlesnakes used in this film were de-fanged and their mouths were sewn shut to keep them from biting people.
Snake wrangler Frank Weed can be seen in the film as a man milking a rattlesnake for its venom.
On the first day of filming, the filmmakers discovered that the cabin intended for use as an exterior had been knocked down. Everyone pitched in to help rebuild the cabin in a hurry.
The home of the character of Richard Thomkins (Alex Rocco) was, in real life, owned by a friend of producer / director William Grefé.