- Families, friends, enemies, and lovers experience life-changing events in the large upstate city of Port Charles, New York, which has a busy hospital, upscale hotel, cozy diner, and dangerous waterfront frequented by the criminal underworld.
- Events in this daytime drama are centered in Port Charles, a community on the coast in western New York. On-going plots are centered around the people who work in General Hospital, people who work in the business community (most notably for the Quartermaines' company E.L.Q.), and some sort of international intrigue involving former Agents of the W.S.B. (World Security Bureau). Big plots of the past include Luke (Anthony Geary) and Laura's (Genie Francis') wedding and Mikkos Cassadine's (John Colicos') evil weather machine.—Ed Sutton <esutton@mindspring.com>
- Skye Quartermaine (Robin Christopher) headlines a show about the residents of Port Charles, New York. Once a show about the drama inside a city hospital, General Hospital has evolved into a show where the hospital has been nearly phased out. Stories focus on the upper-crust Quartermaines, led by Skye Quartermaine, her brothers A.J. (Billy Warlock) and Jason (Steve Burton), father Alan (Stuart Damon), stepmother Monica (Leslie Charleson), and grandparents Edward (John Ingle) and Lila (Anna Lee). Other stories involve mob boss Michael "Sonny" Corinthos (Maurice Bernard), his wife Carly (Laura Wright), and one-time girlfriend Brenda (Vanessa Marcil).—Matthew Callahan
- The General Hospital of today centers on Kelly's Diner, Michael "Sonny" Corinthos' (Maurice Bernard's) penthouse, the Quartermaine house, and sometimes the hospital. Once a show based around the hospital and its employees, it is now centered on the mob. Maurice Bernard headlines the show about some of the residents of the fictitious town of Port Charles, New York. Stories focus on Sonny and how his life affects the people around him, mainly his wife Carly (Laura Wright), his main hit man and best friend Jason Morgan (Steve Burton) (formally Quartermaine) and Sonny's recently acquired twenty-one-year-old sister Courtney (Alicia Leigh Willis). Other story lines that may be featured will focus on the quirky Quartermaines, which include Skye (Robin Christopher), A.J. (Billy Warlock), Ned (Wally Kurth), Edward (John Ingle), and Emily (Natalia Livingston). Promising story lines on the show at the moment are the stories of Elizabeth Webber (Rebecca Herbst) and Richard "Ric" Lansing (Rick Hearst) and the current teen story line.—Mickey
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