The four engine bomber flown by Gable and Tracy near the end of the film was a Boeing Model 299B, Y1B-17 "Flying Fortress". It was one of the 13 Y1B-17s ("Y" indicating service test and "1" indicating procurement from F-1 funds) acquired by the U.S. Army Air Corps for evaluation. The massed flight at the end of the film consisted of all 13 Y1B-17s, which had USAAC serial numbers
36-149 to 36-161, and had been delivered by Boeing between 11 January and 4 August 1937. All were eventually redesignated B-17.
Included among the American Film Institute's 2001 list of 400 movies nominated for the top 100 Most Heart-Pounding American Movies.
After Jim flies away from Ann, he passes over the ballpark where they recently attended a baseball game. Although the movie takes place in Wichita, Kansas, the ballpark shown in the fly over is the old and now demolished Wrigley Field in Los Angeles, California.
Myrna Loy and four crew members were in an automobile accident on their way to do location work in San Diego for this film. In mid-January, 1938, the car in which they were traveling accidentally went off the road after swerving to avoid a stalled truck. Also in the car was Loy's stand-in Shirley Hughes, hairdresser Eleanor Cole, wardrobe girl Margaret Wood, and the unnamed driver; nobody was injured.