Dr. Gillespie (Lionel Barrymore) continues testing Dr. Lee Wong How (Keye Luke) and Dr. Randall Adams (Van Johnson), both vying to be his new assistant. Meanwhile an epidemic breaks out in the hospital children's ward and psycho killer Roy Todwell breaks out of prison just as Gillespie is arguing to the prison board that Roy belongs in a mental hospital. All this plus a double amputee struggles to come to terms with his disability and a beautiful woman throws herself at Dr. Adams.
The third Gillespie movie follows up on the events of Calling Dr. Gillespie. Donna Reed returns and is even lovelier than before. The character of Roy was recast for some reason. The new actor, John Craven, isn't as creepy as the last one, Phil Brown. Craven is just kind of skeevy. Van Johnson and Keye Luke are both fun. Luke is once again given the wartime comments about Japs, as well as the subplot about a man who lost both his legs at Pearl Harbor. Beautiful Marilyn Maxwell has a sexy part as a wealthy hospital volunteer who comes onto Johnson very strongly. She would appear a couple more times in the series. Margaret O'Brien is cute as one of the sick kids. She was such a precocious little actress who did melodrama very well. It's an enjoyable entry in the series with more subplots than you can shake a stick at. Barrymore is terrific as usual.