The Doom Patrol set out for Paraguay where they discover the Nazi doctor who created Mr. Nobody and the connection between the Chief and the two villains.
After a violent outburst from Cliff, the team engages in some self-led group therapy - leading to some growth within the group as they are knit closer together.
A sentient, gender-queer, teleporting street, named Danny is being hunted by the secret Bureau of Normalcy and needs help from Niles - but gets Vic and Larry instead. Meanwhile, Rita and
Larry pays a visit to his long lost-love, while Cliff and Rita travel to Gator Country to reconnect with his daughter. Vic worries about his operating system.