An obstacle was that Sorrentino's usual Italian co-financier Medusa Film, which is controlled by Berlusconi, was not willing to participate in this production.
Filming took place in Rome and Tuscany.
The film came out in theaters in two acts: the first act, called Loro 1, came out on 24 April 2018, while the second act, Loro 2, came out on 10 May 2018.---On 7 August 2018, it was announced a new 145 minutes release of Loro scheduled for 13 September 2018. This new international cut has been made in order to allow the movie to run for the 91st Academy Awards.
The title Loro is Italian for "them", but also a word play on l'oro, meaning "the gold".
Toni Servillo meets Paolo Sorrentino for the fifth time in his career after the director's first film L'uomo in più (2001), The Consequences of Love (2003), Il Divo (2008), winner of the Jury Prize in Cannes and La Grande Bellezza, Oscar for the best foreign film.