The two leads, Lucas Schmidt and Kreig Schmidt, are married in real life. Kreig specifically asked to portray the role of Bryan while Lucas began the casting process.
The script was originally much longer. Several scenes had been deleted prior to filming, including a few scenes taking place in a strip club that Joey owns, scenes taking place in a church when Bryan goes to talk to a priest, and a scene with Bryan dumping a body.
The meth in the film is actually rock candy. The actors simulated smoking it by melting the rock candy, then exhaling cigarette smoke.