While each season is based on Simon Rich's short stories, he asks the cast not to read them, and they all collaborate on their parts through character work.
Based on Simon Rich's book, "What in God's Name."
The theme music is actually a newer piece of music, which is itself based upon Ennio Morricone's original piece for "The Good, The Bad, and The Ugly" soundtrack, entitled "Ecstasy of Gold".
Not only is the casting color blind (there are two sets of siblings of entirely different races, for example), but creator Simon Rich instructed the characters not to even do any accents other than their natural voices.
Alongside the initial series order announcement in May 2017, it was confirmed that Daniel Radcliffe and Owen Wilson would star in the series. On October 19, it was announced Steve Buscemi had replaced Wilson in the role of God after the latter had decided to vacate the part. In November 2017, Deadline Hollywood and Variety reported that Geraldine Viswanathan, Jon Bass, Karan Soni, and Sasha Compère had been cast in series regular roles. On March 25, it was announced that Lolly Adefope had joined the cast in a main role.