"On Wheels" is a road movie, a coming of age drama, aimed at a young audience. Lucas, a 13-year-old boy, is wheelchair bound after suffering an accident. Laís, a 12-year-old girl, helps her mother selling breakfast at a truck stop, in the small town where they live. The girl would love to meet her father, a truck driver who left when she was a child and never returned. Laís and Lucas become friends in school, and when she finds out where her father lives, the two set off on a trip.