Dr. Irène Frachon from Brest discovers, that Mediator pills cause heart valve problems/deaths. In 2009, she starts an uphill battle against the producer and the French health authorities.Dr. Irène Frachon from Brest discovers, that Mediator pills cause heart valve problems/deaths. In 2009, she starts an uphill battle against the producer and the French health authorities.Dr. Irène Frachon from Brest discovers, that Mediator pills cause heart valve problems/deaths. In 2009, she starts an uphill battle against the producer and the French health authorities.