Annie Parker (Samantha Morton) suffers many losses. Her mother, father, and older sister all died from cancer. It's the 1970's. She is obsessed with checking for lumps and eventually she also gets breast cancer. Her husband Paul (Aaron Paul) is a pool cleaner. Louise (Alice Eve) is her younger sister. Dr. Gold (Corey Stoll) suspects a genetic cause but he is refuted by more experienced doctor. At UC Berkeley, research genetic scientist Mary-Claire King (Helen Hunt) is trying to map the human genome but the task is overwhelming. Her team is on a long, winding search for the cause of breast cancer and the discovery of the responsible gene.
Morton and her side of the story is very compelling with surprising humor and infinite humanity. The Helen Hunt side is less compelling. I can think of several ways to increase the tension but her side is inherently less dramatic. It's more scientific and less humane. It could have enlightened some of the science but that may be asking too much. It leaves me to wonder if concentrating solely on Annie Parker would be more intriguing.