- Speaks Portuguese fluently.
- Riverdale (2017) was her first acting job.
- Attended New York University at the same time as her Riverdale (2017) co-star, Cole Sprouse, although they did not know each other at school.
- Her parents moved from Brazil to the U.S., and Camila lived in Brazil for a year when she was ten.
- She had to dye her hair darker to play Veronica Lodge on Riverdale (2017).
- Booked her role on Riverdale (2017) while still a student at New York University's Tisch School of Arts. She graduated in May of 2016.
- Met her boyfriend Rudy Mancuso while filming Mùscia.
- While attending New York University, Mendes became friends with fellow actress Rachel Matthews and musician Maggie Rogers. Both Mendes and Matthews would go on to appear in Rogers' music video for "Give A Little".
- She was originally cast for I Know What You Did Last Summer (2025) but have to dropped out due of her scheduling conflicts with Masters of the Universe (2026).
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