- Has two daughters - Kalyn (b. 1989) and Bailey DeLuca Baio (b. November 2, 2007) with her husband Scott Baio. Renee was pregnant with twins, however, lost Bailey's twin at 17 weeks pregnant.
- Was Pamela Anderson's body double in Baywatch (1989).
- Body double and stunt woman, swimsuit model, and a business owner of Whipped Couture, Bel-Air Bling, and Sloan's Stones. Holds an MBA in Business and studied at LSE.
- Renee is Native American & Dutch. She is the daughter of William and Beverly, has a younger sister named Brandy, and an older brother named Bryan.
- In mid June 2015 she was diagnosed with meningioma brain tumor. As of March 10, 2018 she has two meningioma brain tumors and also was diagnosed with microvascular brain disease in October 2017.
- On September 14, 2007 Renee married her boyfriend, actor Scott Baio after 3 years of dating and a year-long engagement.
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