- He is an accomplished magician specializing in the art of sleight-of-hand.
- In his senior year of high school, he won a prize at his school for his Halloween costume - he dressed as silent film legend Charles Chaplin.
- Graduated from Christian Brothers Academy in Lincroft, New Jersey, USA in 2003.
- Has two brothers, actor Adam Pucci and drummer Zak Pucci.
- Reunited with Vincent D'Onofrio, who played his father in Thumbsucker (2005), in Cruise to Nowhere (2006).
- He was very involved in his high school's theater, Pegasus Productions. He played Billy in his school's production of Cole Porter's "Anything Goes" and the Jesus character in the school's production of "Godspell". He also portrayed Ebenezer Scrooge in a student-run production of "A Christmas Carol".
- Has a younger sister named "Penelope Ann" after a character in the musical "Bye, Bye, Birdie", but everyone calls her "Poo".
- After returning from the 2009 Sundance Film Festival where 3 of his films premiered, The Answer Man (2009), Brief Interviews with Hideous Men (2009) and The Informers (2008) and being a juror for the Short Film Competition, is enjoying his new apartment in Venice, California. (February 2009)
- In Philadelphia, Pennsylvania, USA while shooting Mark Webber and Jim Jarmusch's Explicit Ills (2008). (September 2007)
- In Arlington, Texas, USA shooting a movie called Brotherhood (2010), which also stars his friends, Trevor Morgan and Jon Foster. (August 2008)
- In Los Angeles to film the role of "Lee" in The Chumscrubber (2005). (March 2004)
- In New Mexico, USA filming the Pastor Brothers (David Pastor and Àlex Pastor) movie Carriers (2009). (September 2006)
- In Los Angeles after filming Southland Tales (2006) and Green Day: Jesus of Suburbia (2005), Lou is rehearsing for the lead in Martin Hynes' The Go-Getter (2007) and also for a part in Richard Linklater's Fast Food Nation (2006). (October 2005)
- After attending the Sundance Film Festival in Park City, Utah, USA in January to promote The Go-Getter (2007), he is now in Winnipeg, Manitoba, Canada filming Horsemen (2009) with Dennis Quaid. (February 2007)
- In Waterville, Maine, USA filming Empire Falls (2005). (September 2003)
- In Los Angeles doing reshoots for Carriers (2009) and shooting The Informers (2008). (October 2007)
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