- Benaderet became sick with cancer in 1967, which led to her leaving Petticoat Junction (1963) in what it was hoped would be a temporary retirement. Rosemary DeCamp was brought in to play the Bradley girls' Aunt Helen in the scripts that were obviously written for Benaderet's character, Kate Bradley. Benaderet only managed to return twice on the show after her departure. Following her death, June Lockhart was brought in as a surrogate mother figure and lady M.D. who sets up practice at the Shady Rest Hotel. However, Benaderet's anchoring presence was missed by the public and the show lasted only two more seasons (1968-1970).
- A prolific dialectician, she was one of the few female voice artists associated with Warner Bros. studio in its early days (as Mel Blanc provided the majority of character voices at the time, even for the female characters). She never received screen credit due to Blanc's WB contract. She went on to play the character Granny from 1937 into the 1950s when June Foray took over the vocal role. She reunited with Blanc in the 1960s when he voiced Barney Rubble to her Betty Rubble.
- Bea Benaderet was Lucille Ball's original choice for the role of Ethel Mertz on the sitcom I Love Lucy (1951).
- Though rarely credited, Bea Benaderet was the voice of several female characters in many Warner Bros. Looney Tunes and Merrie Melodies cartoons.
- She died during the run of her television series Petticoat Junction (1963), and a stand-in, seen only from the back, and with no dialogue to speak, was used for the last episode in which she supposedly appeared.
- She was one of producer/creator Paul Henning's favorite character actresses. When developing The Beverly Hillbillies (1962), he kept Bea in mind, and, although she was interested in the role of Granny, Henning felt she was too busty for the role. During auditions for the role of Granny, it was Benaderet who pointed to Irene Ryan and told Henning, "There's your 'Granny'!".
- Was considered for the role of Granny on The Beverly Hillbillies (1962), but got the role of Cousin Pearl Bodine instead.
- Her second husband, Gene Twombly, a sound-effects technician (both worked on The Jack Benny Program (1950)), died of a heart attack just four days after she died of cancer.
- In 1936, she joined Orson Welles on radio's "The Campbell Playhouse" and received her first big break when she became a regular on Jack Benny's big radio show, where she created memorable characters such as Gertrude Gearshift. A major radio staple at the time, her numerous appearances included the comedies "The Adventures of Ozzie and Harriet", "The Great Gildersleeve" and "Fibber McGee and Molly". She also played Lucille Ball's best friend on radio's "My Favorite Husband", which was the precursor to television's I Love Lucy (1951).
- After her death of emphysema at age 62, Bea was interred at Pierce Brothers Valhalla Memorial Park in North Hollywood, California. Her second husband, Gene Twombly, died four days later (October 17, 1968) of a heart attack and was interred next to her.
- Born in New York City and raised in San Francisco, Bea was discovered by the manager of radio station KGO, who spotted her singing in a children's production of The Beggar's Opera, and put her on the radio as a singer.
- Her father, Samuel David Benaderet, was a Turkish Jewish immigrant. Her mother's maiden name was Margaret O'Keefe. Bea had two children, Jack and Maggie, from her first marriage, to actor Jim Bannon.
- You would never guess it from her wholesome television and radio appearances, but Bea could outcuss a navy boatswain. She would crack up her cast members on The Jack Benny Program (1950) by betting on which lines announcer Don Wilson would screw up on each show.
- She was awarded a Star on the Hollywood Walk of Fame at 1611 Vine Street on Hollywood Boulevard in Hollywood, California on February 8, 1960.
- While attending the Reginald Travis School of Acting in San Francisco, she appeared with stock companies and little theaters, finding occasional employment as an actress, singer, writer, producer and announcer on radio.
- All of her Warner Bros. cartoon characters were taken over by June Foray after she left Termite Terrace.
- Attended St. Rose Academy High School and began her acting studies at the Reginald Travis School of Acting in San Francisco.
- Was the voice, and distinctive laugh, of Witch Hazel in several Bugs Bunny cartoons, e.g., 1954's "Bewitched Bunny".
- Step-grandmother of Tom Fridley and Molly Fridley.
- In a nod to Bea's husband's name, Paul Henning named Mrs. Drysdale's psychiatrist Dr. Twombly. Jethro had to get a health certificate to go to school, and ended up being analyzed on Dr. Twombly's couch.
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