- When he won his Oscar for Almost Famous (2000), he dedicated the award to "Audrey and Billy". Most people assumed this was for Audrey Hepburn and Billy Wilder but, in fact, it was for Billy Wilder and his wife Audrey Young, who were close personal friends of Cameron.
- Admires Billy Wilder very much and uses a lot of what Wilder taught him in his films. In addition, his favorite movie is Wilder's The Apartment (1960).
- He wrote the screenplay to Fast Times at Ridgemont High (1982) based on his book. He wrote the book after posing as a student at Hollywood High School, the school that everyone from his side of the tracks wanted to attend.
- Directed four actors in Oscar-nominated performances: Tom Cruise, Cuba Gooding Jr., Kate Hudson, and Frances McDormand. Gooding Jr. won the Oscar for Best Supporting Actor for his performance for Jerry Maguire (1996).
- Steven Spielberg did a cameo in Crowe's Vanilla Sky (2001) and Crowe did a cameo in Spielberg's Minority Report (2002); both films starred Tom Cruise.
- Wrote the liner notes for Lynyrd Skynyrd's "One More From the Road" album.
- Often refers to the novel "To Kill a Mockingbird" in his films.
- Wrote liner notes for Peter Frampton's breakthrough album "Frampton Comes Alive".
- His wife is Nancy Wilson from the rock group Heart.
- Wrote the liner notes for "Biograph" by Bob Dylan.
- Former journalist for Rolling Stone magazine.
- Early career as a journalist included 4 years as the rock music critic for the San Diego Union (the city's major daily).
- Wrote liner notes for Led Zeppelin's "The Song Remains The Same" live record.
- Wrote the liner notes for "Anthology: Through the Years" by Tom Petty and the Heartbreakers.
- Frequently collaborates with set decorator and production designer, Clay A. Griffith. They have worked together on Say Anything (1989), Singles (1992), Jerry Maguire (1996), Almost Famous (2000), Elizabethtown (2005), We Bought a Zoo (2011), Aloha (2015) and Roadies (2016).
- Son of Alice Marie Crowe.
- Father of twins, William James Crowe and Curtis Wilson Crowe born on January 23, 2000.
- Writing his next movie, with an ensemble cast of eight lead roles. That script is still as-yet "Untitled". Also, writing a biopic of music producer Phil Spector, which he and Tom Cruise have long been planning to make. (July 2002)
- Member of the jury at the Venice Film Festival in 2006.
- (Late September 2010) Nancy Wilson filed for divorce citing "irreconcilable differences". She listed June 15, 2008, as their date of separation.
- Despite being a successful author, screenwriter, journalist, producer and director, did not complete college. Dropped out of San Diego city college to pursue his career.
- He and his wife have 4 springer spaniels.
- Attended University of San Diego High School.
- His father was from Stanton, Kentucky and his mother is from San Bernardino, California. His father had English and Scottish ancestry, while Cameron's mother is of half Greek and half Spanish descent.
- Wrote the foreword for "Ready When You Are, Mr. Coppola, Mr. Spielberg, Mr. Crowe" by Jerry Ziesmer (Scarecrow Press, 2003).
- Ex-brother-in-law of Ann Wilson and Lynn Wilson.
- Five of the films that he directed (Say Anything (1989), Singles (1992), Jerry Maguire (1996), Almost Famous (1996) and Elizabethtown (2005)) have scenes with characters on airplanes or walking through airports.
- Attended Indio High School.
- Attended San Diego City College.
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