- She appeared on Family Feud (1976) with her family in 1981 (and won the $10,000 grand prize!).
- Is of Lebanese heritage.
- Won Celebrity Poker Showdown (2003) championship. (September 2005)
- In the King of the Hill episode 'Are you there God? It's me, Margaret Hill', Kathy Najimy's character Peggy impersonates a nun to get a teaching job at a Catholic school. When Hank finds out, he says 'At least when Whoopi Goldberg did it she was avoiding gangsters', in reference to the 1992 movie Sister Act. Najimy was also in Sister Act as a nun.
- Appeared on the The $25,000 Pyramid (1982) where she won a Commodore 64 home computer but no money.
- She appeared as her Sister Act (1992) character in Lady Soul's "If My Sister's In Trouble" music video.
- Participated in Larry King's book, Remember Me When I'm Gone, where celebrities write their own gravestone epitaphs.
- During a 20th anniversary screening of "Hocus Pocus", Najimy admitted that she believes in white magic.
- Won Gameshow Marathon (2006)
- Daughter, Samia Najimy Finnerty was born 12 December 1996.
- She played a character, named "Olive Massery", on Veronica's Closet (1997). Massery is her mother's maiden name.
- Surname is pronounced "NUH-jee-me".
- Has been a Gay and Lesbian rights activist since age 18.
- Comedy partners with Mo Gaffney.
- Kathy Najimy was a contestant on a 1986 episode of The New $25,000 Pyramid. Her celebrity partners that week were Constance McCashin of Knots Landing, along with LeVar Burton. She lost both games and never made it to the Winners Circle. This episode aired on October 5th, 2017. The original air date is unknown.
- She is a staunch liberal Democrat and LGBT rights activist.
- Appeared as the fairy godmother in the Rebecca Lynn Howard video for "When My Dreams Come True".
- Close friends with her Sister Act co-star Wendy Makkena.
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