- In Barbara Walters: Her Story (2014), Walters says her infamous '01 interview with Heche on 20/20 (1978) is the weirdest interview she's ever done.
- After a number of personal bankruptcies and a particularly nasty divorce from her husband, Heche was filmed on a news program publicly screaming that she was being victimized by her husband for custody battles and her television studio over the cancellation of her TV series Men in Trees (2006). As of the late 2000s, she claimed she was almost homeless and broke.
- Heche, scantily clad, was picked up by police at a rural home in Cantua Creek, California after telling occupants she was looking for a spaceship that was supposed to be meeting her there. The actress spent the night strapped to a gurney at Fresno University Medical Center's psychiatric unit and was released the next morning after being seen by doctors for two hours. (August 19, 2000)
- Tried and said she benefited from LSD therapy for mental health.
- Lived with Thomas Jane from 2019 to 2021.
- Gave birth to her second child, Atlas Heche Tupper, on March 7, 2009. He weighed 6 lbs. 12 oz. Dad is boyfriend, James Tupper.
- Nominated for Broadway's 2004 Tony Award as Best Actress (Play) for a revival of "Twentieth Century".
- Said on her radio show that she was under the influence of magic mushrooms the night she met her ex-girlfriend Ellen DeGeneres.
- Youngest of five children. Sister Abigail was involved in prostitution for a while but now designs jewelry in New York. Their three siblings are deceased.
- 4 September 2001: Autobiography "Call Me Crazy" released. Heche wrote it in just 6 weeks.
- While promoting Return to Paradise (1998) on Entertainment Tonight, Heche was asked to respond to reports that she may have been romantically involved with co-star Vince Vaughn while making the film overseas. Heche, who lived an openly gay life with Ellen DeGeneres, was insulted by the question, cut short the interview, and left with the tape.
- Her late sister Susan Bergman wrote a book called "Anonymity: The Secret Life of an American Family" (1994).
- 2 March 2002: 7 pound boy, Homer Heche Laffoon, born in Los Angeles. The baby was the first child for Heche and her husband, cameraman Coleman 'Coley' Laffoon.
- During an interview with Barbara Walters, Heche stated that she had an alter ego named Celestia. (September 5, 2001)
- Split with boyfriend James Tupper after 11 years together. (January 11, 2018)
- Surname is pronounced "Haysh".
- Before "coming out" she dated producer Neal H. Moritz, 24-years-older comedian Steve Martin and small time actors Richard Burgi and Bill Cusack.
- Starred in Pulitzer Prize-winning drama 'Proof' on Broadway. (July 2002)
- Chosen by People Magazine as one of the 50 most beautiful people in the world. (1998)
- She believed that she destroyed her burgeoning career in the late 1990s, not necessarily by dating Ellen DeGeneres, but by going public with the relationship only days into its growth, when she was not yet an established actress.
- Was the basis for the Heather Graham character in Bowfinger (1999).
- Was introduced to former girlfriend Ellen DeGeneres by Vince Vaughn and writer Roger Friedman on March 23, 1997 at Morton's Steakhouse in West Hollywood. The couple broke up August 16, 2000.
- Announced that she was engaged to her boyfriend, cameraman Coleman 'Coley' Laffoon. (May 30, 2001)
- Lindsey Buckingham and Neale Heywood have written a song called "Come" about her, taking shots at her lesbianism and delusions. (2003)
- Announced that she intended to marry Ellen DeGeneres if Vermont carried through its plans to legalize gay marriages. (October 1999)
- She was the aunt of Elliot Bergman and Natalie Bergman, who are the music group Wild Belle. Their mother was Anne's older sister, author Susan Heche Bergman (1957-2006), who died of brain cancer. Their father is Judson Bergman. Susan and Judson married in 1979 and had two other children, daughter Elise and son Bennet.
- Co-hosted a radio show on SiriusXM called "Love and Heche" with Jason Ellis.
- Her Christian mother, Nancy, claimed to have cured her lesbianism by praying for her.
- Heche's family moved 11 times before she was 12.
- Auditioned for the role in I'm Not There (2007) that went to Cate Blanchett.
- Went to Ocean City High School, Ocean City, New Jersey. Graduated from the Francis W. Parker School, Chicago, Illinois.
- Returned to work 8 days after giving birth to her son Atlas in order to begin filming episodes of Hung (2009).
- Had a butterfly tattoo on her lower back.
- She was the daughter of Nancy Abigail (Prickett) and Donald Joe Heche. She was of one quarter Swiss-German and one eighth Norwegian descent, with her other ancestry having been German, English, Scottish, and more distant Scots-Irish/Northern Irish and Welsh. Her surname comes from her paternal great-grandfather Emanuel Heche, who was born in Bern, Switzerland.
- Two movies she starred in that were released posthumously, "13 Minutes" and "Supercell" both had to do with tornadic weather.
- Appearing as a regular guest star on the TV show Everwood (2002). (March 2005)
- Finished pilot for her new ABC series, Men in Trees (2006). (March 2006)
- Her last reported romantic attachment was with Ami Goodheart.
- Auditioned for the role of Giselle in Enchanted (2007) which ended up going to Amy Adams.
- Was in Vancouver, Canada filming the first season of Men in Trees (2006). (July 2006)
- Once hit on Francesca Gregorini. The advances were refused.
- She was born at 4:51 PM (EDT).
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