52 wins & 60 nominations
- 1999 Winner American Comedy Award
- Funniest Female Performer in a TV Special (Leading or Supporting) Network, Cable or Syndication
Tied with Rosie O'Donnell for The 52nd Annual Tony Awards (1998). - 1990 Winner American Comedy Award
- Funniest Female Performer in a TV Special (Leading or Supporting) Network, Cable or Syndication
- 2019 Nominee Daytime Emmy
- Outstanding Entertainment Talk Show
Shared with: Mark Bracco · Mike Mahan · Izzie Pick Ibarra · Steve Sauer · Allen Shapiro · Nikki Varhely-Gillingham · Linda Gierahn · Suzy Ratner · Scott Gawlik · Lexi Shoemaker · Theresa Moore King
- 2023 Winner Primetime Emmy
- Outstanding Variety Special (Pre-Recorded)
Shared with: Baz Halpin · Brian Miller · Steve Sauer · Theresa Moore King · Paul Miller · Linda Gierahn · Mark Bracco · Jenessa Salcedo - 2018 Nominee Primetime Emmy
- Outstanding Variety Special (Pre-Recorded)
Shared with: Linda Gierahn · Ben Roy · Leslie Kolins Small · Paul Miller · Mark Bracco · Mike Mahan · Allen Shapiro · Steve Sauer - 2009 Nominee Primetime Emmy
- Outstanding Guest Actress in a Drama Series
For playing "Bridget 'Birdie' Sulloway". For episode "Ballerina".
- 1970 Winner Golden Apple
- Female Star of the Year
- 1991 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 1983 Nominee Golden Globe
- Best Performance by an Actress in a Miniseries or Motion Picture Made for Television
- 2017 Winner Grammy
- Best Spoken Word Album
In Such Good Company: Eleven Years Of Laughter, Mayhem, And Fun In The Sandbox - 2011 Nominee Grammy
- Best Spoken Word Album (Includes Poetry, Audio Books & Storytelling)
For "This Time Together: Laughter And Reflection"
- 1991 Winner People's Choice Award
- Favorite Female Performer in a New TV Series
- 1981 Winner People's Choice Award
- Favorite All-Around Female Entertainer
- 1981 Winner People's Choice Award
- Favorite Female TV Performer
- 1980 Winner People's Choice Award
- Favorite All-Around Female Entertainer
- 1980 Winner People's Choice Award
- Favorite Female TV Performer
- 2024 Nominee PGA Award
- Outstanding Producer of Live Entertainment, Variety, Sketch, Standup & Talk Television
Shared with: Steve Sauer · Theresa Moore King · Linda Gierahn · Brian Miller · Mark Bracco · Baz Halpin · Paul Miller
- 1979 Nominee Gold Medal
- Favorite Variety Star
- 1975 Nominee Gold Medal
- Variety Star
- 1974 Nominee Gold Medal
- Variety Star
- 1973 Nominee Gold Medal
- Variety Star
- 1967 Nominee Gold Medal
- Favorite Comedy Star
- 1962 Winner Ace Award
- Amateur Cartoonist Extraordinary
- 2009 Nominee OFTA Television Award
- Best Guest Actress in a Drama Series
- 2013 Nominee BTVA Anime Dub Movie/Special Voice Acting Award
- Best Vocal Ensemble in an Anime Feature Film/Special
Shared with: Bridgit Mendler · David Henrie · Will Arnett · Amy Poehler · Moises Arias · Gracie Moore
- 2007 Winner Gold Derby TV Award
- Life Achievement (Performer)
- 2013 Winner Mark Twain Prize
- Mark Twain Prize for American Humor
- 2016 Winner Texas Film Hall of Fame
- Texas Film Hall Of Fame
- 2022 Nominee Pena de Prata
- Best Ensemble in a Drama Series
Shared with: Bob Odenkirk · Giancarlo Esposito · Jonathan Banks · Michael Mando · Patrick Fabian · Rhea Seehorn · Tony Dalton
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