- Was the first African-American to "star" in a film.
- Holding a law degree from Pennsylvania's Dickinson University, Clarence requested that he be addressed as Dr. Muse in later years.
- An outspoken proponent for the positive treatment of black performers, Muse fought demeaning stereotypes for most his career. Ironically, he was a staunch supporter of the controversial black-oriented TV series The Amos 'n Andy Show (1951). He insisted that, despite the standard caricatures of the title players, the series allowed black actors to portray white-collar roles such as doctors, bankers, judges, and professors, generally not done in white-oriented series.
- In his salad days, Muse appeared as an opera singer, a minstrel performer and a vaudeville actor. He also composed songs and wrote plays and sketches, and was considered a pioneer in the 'black theatre' movement.
- Was the first black director of a Broadway show in 1943, "Run Little Chillun", described as a 'negro folk play with music'.
- Died four days before the release of his final film, The Black Stallion (1979).
- A member of Phi Beta Sigma Fraternity, Inc., Omega Chapter.
- Was a founder of the Harlem Lafayette Theatre and a member of the Lafayette Players.
- Inducted into the "Black Filmmakers Hall Of Fame" (1973)
- Sunday, May 2nd, 1937: He was a special guest on the Los Angeles-based radio program "Help Thy Neighbor" hosted by Hal Styles.
- Died one day before his 90th birthday.
- His mini-bio says otherwise but Clarence Muse, who died in 1979, was not in "Casino" 1995.
- Father: Alexander Muse; Mother: Mary A. Kellam.
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