8 wins & 25 nominations
- 2001 Winner American Comedy Award
- Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 2003 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 2002 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 2001 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 2002 Nominee Golden Satellite Award
- Best Performance by an Actress in a Series, Comedy or Musical
- 2004 Nominee Young Artist Award
- Most Popular Mom & Pop in a Television Series
Shared with: Bryan Cranston
- 2014 Nominee BTVA Television Voice Acting Award
- Best Vocal Ensemble in a Television Series - Children's/Educational
Shared with: Cameron Boyce · Madison Pettis · Jonathan Morgan Heit · Corey Burton · Jeff Bennett · Loren Hoskins · Dee Bradley Baker · Ariel Winter · Russi Taylor
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