Lovers of action movies, fans of TV series like '24', readers of Robert Ludlum novels and similar have good chances to like this movie. It starts very well, with three mysterious virus-related deaths and a failed transaction of bio-weapons in Berlin that leaves as well its dose or corpses and evolutes quickly in a national crisis type of story, sort of a combination between 'Outbreak' and '24'.
The film is well done, well acted, the pace of the action does not trail almost at all and the story has the kind of logic you would expect from such stories. The principal problem may be the format - the two and half hours are too long for a feature film (although we have seen many similar length films lately on big screens) and two short for a TV series.
The professionalism of filming and acting lends more on the feature film side. Stephen Dorff in the principal role is credible and likable, and the principal critic one can bring to his act is that he looks so much as Jack Bauer. Mira Sorvino, Sophia Myles, Blair Underwood, Colm Meaney are all at their place and give credible acts. The only mis-casting seemed to me to be Anjelica Houston, which did not seem to be very comfortable as a Madam President.
It's not great cinema, just fair entertainment. Action movie fans should not miss this film, the other can skip it without problems.