If certain theatrical films, like "the Lion King", "Finding Nemo", and "Kung Fu Panda", can be very successful and memorable in characterization and storytelling, then TV movies can be like that, too. And "Ed, Edd n Eddy's Big Picture Show" is one superb example.
Basically, the movie centers on the Eds searching for Eddy's brother after Eddy's latest scam backfires big time. (Only the Eds fans know exactly why the scam flops out - sort of.) And all the kids of the Cul-De-Sac have to track them down to avenge for themselves before those troublemakers can reach their destination. Aside from maniac animation and ultimate level of humor, there's one thing that hasn't been overlooked throughout the whole film: heart.
The story of "Ed, Edd n Eddy's Picture Show" has been split into many parts: the Eds, Kevin and Nazz, Jonny and Plank, Sarah and Jimmy (later merged with the Kanker Sisters and Wilbur), and Rolf and Wilbur. But unlike "Madagascar: Escape 2 Africa", there's a sufficient amount of story for each set of characters - not too much nor too little. It's all because of the superb sense of direction of the movie. Even the film is almost well-structured, too. (The beginning is a perfect example!) And it seems that the creative artists of "Ed, Edd n Eddy" had managed to take the TV movie to "the place it has to be" big time.
So if you are looking for TV movies with superb comedy and heart, like "Escape from Cluster Prime" and "Rugrats: All Growed Up", then "Ed, Edd n Eddy's Big Picture Show" is one best example to see.