Jonathan Mann wurde am 30 Juli 1947 in Boston, Massachusetts, USA geboren. Er war mit Mary Lou Clements und Marie-Paule Bondat verheiratet. Er starb am 2 September 1998 in Kanada.
With his wife Dr. Mary Lou Clements-Mann died in the crash of Swissair Flight 111 off the coast of Nova Scotia. They were on their way to Geneva to attend WHO/UN-sponsored strategy sessions on AIDS.