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Shelly returns home and reminisces about a soul-shaking memory of when her 8-year-old sister suddenly fell terribly ill. Guided by her grandmother, Shelly and her family go on a solemn, spiritual journey to honor the past, preserve their history and bridge cultural divides.

The Letter 'D' is a poignant exploration of Mildred's struggles with memory loss. As this former preschool teacher wrestles with early signs of dementia, she becomes increasingly confused and paranoid, suspecting her loving daughters of ulterior motives. Through a series of flashbacks, Mildred's gradual decline is revealed, making it clear that she is losing her grip on reality and independence. The film delicately examines family bonds, memory, and the heart-wrenching decisions faced by loved ones when a family member can no longer safely live on their own.