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Staying as close to the novel as much as possible. Victor Frankenstein creates a chemical that could bring the dead back to life.

On October 31, 2010 a big company called Horizex released a virus in a small town. 3,000 people died in 12 hours and now a group of friends and a news reporter video tape the army of the undead.

Jade, her sister Ophelia, and brother Bryce, are the last three vampires in the world. They come into this small town to figure out a plan to restore their bloodline and raise an army of vampires. Jade says she needs someone with pure and innocent blood to restore balance to the family and for Jade to take over the world. Bryce finds a young girl named Brie, who is exactly what Jade wants. The one thing standing in the way of Jade's plan, is the group of vampire hunters that just moved in next to Brie's house. The Hunters are lead by Archer, and is followed by Karver, Riley, and Ash. Their lone goal is to protect Brie from Jade and her siblings and finally put an end to the vampires.

Horizex sends in a team of six marines to fight the army of the undead.

As all of their friends come back from their first semester at college, Thomas (Thomas Sloan) and Nathan (Nathan Pelland) decide to have one last big party together. Everything seems fine until a prank the two boys pull goes wrong and all of the kids find themselves at the hands of a mysterious killer.