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Tenma, a brilliant neurosurgeon with a promising future, risks his career to save the life of a critically wounded young boy. The boy, now a charismatic young man, reappears 9 years later in the midst of a string of unusual serial murders.

A year has passed since Guts parted ways with Griffith. The Band of the Hawk is plotting a rescue mission to save Griffith who is confined to prison.

In 1860s Britain, a boy inventor finds himself caught in the middle of a deadly conflict over a revolutionary advance in steam power.

Red was once a member of the Hero's party, a powerful group destined to save the world from the evil forces of Taraxon, the Raging Demon Lord. That is, until one of his comrades kicked him out.

Kirby crashes onto Planet Popstar and befriends the villagers that live In Cappytown. Unfortunately, King Dedede, the greedy ruler and Escargon, his assistant, aren't happy with that and do whatever they can to drive him out.

Set in 1969, Tokyo. Earth is under the attack by secret creatures known as the Invaders. The only thing, stopping them from controlling the world is A.E.G.I.S, a group of gifted gatekeepers.

Lord Keiro, the Shogun of the Xian Empire, blazes a trail of terror while seeking the sacred sword that will make him a god. Standing in his way is Taito, a powerful star reborn in human form who vows to use his strength to avenge those slaughtered by Keiro. To complete his journey, Taito must seek others like him: the seven star-born warriors with the strength to shatter a corrupt empire.

Cynical, gun-toting monk Genjo Sanzo and his unruly band of misfits to head into the heart of demon territory to stop the experiments to revive Gyomaoh.

Deep in the deserts of southwestern United States lies "Neo Purgatory." Formerly a nuclear waste disposal site, the facility has been turned into a prison for hardened criminals; that is, until the prisoners weaponize the nuclear waste and riot, turning Neo Purgatory into an international disaster. Maki Aoba, Doris Nicholas, Marilyn Moreau, and Naomi Jones make up the "Guard of Rose," an all-female special police task force. Along with stowaway Katherine Hook and multi-purpose robot Link, the Guard of Rose is on patrol investigating rumors of an "angel" near Neo Purgatory when their helicopter is shot down. As the crisis within the prison rapidly devolves, the Guard of Rose members might be the only ones who can stop the prisoners before they unleash nuclear armageddon.

Cacao, a young student, finds that he might be a powerful magic user.

Menchi runs away from Excel's apartment and joins a group a strays who try to return her to her old owner.

A second Ropponmatsu unit appears, but this time in the form of a young, irritating cat-girl who gets on everyone's nerves. When a second bomb appears in F City from ACROSS (disguised as a panda no less), it is up to Ropponmatsu 2 to save the day.

Excel and Hyatt infiltrate city hall, where they stumble upon the wheeling and dealing world of the F City government.

Key, a visually appealing musician, arrives at the ACROSS base to deliver (or rather sing) a message from ACROSS HQ to Lord Ilpalazzo. However due to lack of inspiration, Key is unable to deliver the message. Frustrated (and jealous), Ilpalazzo orders Excel and Hyatt to look after Key until he is able to deliver the message.

Il Palazzo has gained superhuman strength, and battles both the Daitenzin and Excel, who is seeking answers after regaining her memory. Meanwhile, Pedro, Sandora, Nabeshin, and his fallen comrades face off against That Man in a final battle.

Kirby crashes into Pupupu Land, meets new faces and destroys octacon, a monster sent by Holy Nightmare.

First, a typhoon is coming! With Shinobu stuck at Kaede's house, the ninja manor turns into a terrible sausage fest! Witness Onsokumaru's darkest hour!

Cossette returns as the third member of ACROSS, and gives Excel and Hyatt a potion which causes the two to switch bodies. This results in hilarious hijinks, as Watanabe takes Hyatt (in Excel's body) to a love hotel, and Excel (in Hyatt's body) adjusts to a far weaker body. Meanwhile, Nabeshin chases That Man's clones, and Il Palazzo plays guitar with the Mohawks on his three day break.

Tenma learns that Johan used to be in an orphanage known as Kinderheim 511, where he meets an injured boy named Dieter and a former East German official named Hartmann who used to work there.

While Dr. Tenma investigates the serial murders of middle-aged, childless couples and Johan's true identity, law student Nina Fortner receives poetic emails from a stranger.