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Common people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.

Brash, stubborn and resourceful ME Jordan Cavanaugh revives her career in Boston, occasionally breaking the rules and ticking off the cops or her co-workers. On the home front, she gets crime-solving help from her retired-cop dad.

A year ago, a terrorist attack in Odessa, Texas left the city decimated. Blamed for the tragic event, those with extraordinary abilities are in hiding or on the run from those with nefarious motives.

A widower struggling to raise his emotionally challenged son discovers that he can predict events before they happen.

Peter, an FBI agent stationed in Jerusalem who, while investigating a murder of a young female archaeologist, uncovers a conspiracy 2000 years in the making.

On a trip home to Kewaunee, Wisconsin a body falls from the undercarriage of a plane and lands beside Woody. It turns out to be the body of his former mentor - Sheriff Cody. He follows the evidence to Los Angeles but finds that he's not the only one that wants to solve the case.

When evidence unexpectedly appears at a murder scene Woody has been investigating, he is accused of planting it. Bug and Nigel argue over a possible alien abduction case.

A seemingly random mass shooting has Woody and Jordan searching for a motive until the FBI reveals the shooter's identity and his link to a drug kingpin.

Jordan looks into a suspected mercy killing and also hears from her estranged grandmother. Garrett and Trey puzzle over a concentration camp victim's death. Garrett's ex-wife's partner leaves her. A reality show is considering setting a series in the morgue: could Bug or Nigel become its star?

When a mysterious blackout hits the city, Jordan and Bug find themselves trapped in the middle of a multi-car pile-up in the Ted Williams Tunnel.

Macy and Peter, while responding to a call, come across a man who was hit by a car. Macy helps him while Peter freezes. Later Macy learns that the man who they turned over to some paramedics died upon arriving at the hospital. When he goes to speak to the ER doctor, the man refuses to discuss anything with Macy. He later discovers that several other accident victims died upon arriving at the same hospital. Woody and Bug look into the death of a journalist. They believe that his death may be linked to a story of his about a prostitute. A man arrives believing that the prostitute the journalist wrote about could be his daughter.

Jordan and Bug team up with a new, obnoxious detective to investigate the murder of a man who only hours before was on a blind date with Jordan. Meanwhile, after a train car separates and ends up in the river, Garret and Lily work together to track down the families of the victims and Nigel must deal with survivor's guilt after narrowly missing becoming one of them.

Jordan and Detective Lois Carver team up to investigate the death of a senator's daughter and cross paths with a pushy reporter. Bug and Nigel try to respect Jewish law while looking into the death of a man involved in an automobile accident. Macy wrestles with spirituality vs. legality in the case of a transvestite with a special request upon her death.

An elite group of fire fighters are killed in a wild fire and a man falls on Dr. Mahesh "Bug" Vijayaraghavensatanaryanamurthy's (Ravi Kapoor) new sports car.

The bodies of a mother and her two young sons leads to a triple-homicide investigation.

When a veteran cop is murdered in the line of duty, Jordan leads the police and vengeful Detective Eddy Winslow - Max's former partner - to a possible suspect. But after the shooter dies in police custody, Garrett must launch a coroner's investigation to see if Det. Winslow went too far while making the arrest. Elsewhere, Garrett opts to forgo his annual Christmas feast with his ex-wife, Maggie and join Lily for a Thai dining experience, angering his daughter, Abby, while Trey worries if Nigel's invitation for a weekend on the ski slopes also includes a slalom under the sheets.

Woody believes that they have in custody a serial killer who was active years ago who stopped but appears to be active, who was arrested on a different matter. So he asks Macy and Jordan to come up with some forensic evidence that could be link him to the murder. Woody has to deal with the ambitious detective, who arrested him. And Bug is trying to help Detective Seeley locate some crucial evidence which was devoured by a cat.

Jordan teams up with the new M.E., Elaine, and finds herself in the middle of an ATF power struggle, when she investigates the death of Wendy Marsh, wife of alleged Unabomber-style terrorist and former ATF agent Lester Marsh - whose grief and rage over the personal vendetta held against him by a former partner Agent Hawkes, pushes him to strap on some homemade explosives and hold the morgue hostage. Meanwhile, a personal quest for love in the crypt and some friendly advice drives a wedge between long-time mates, Bug and Nigel.

Jordan teams up with the FBI to look into a supposed murder-suicide that took place at a strip club owned by the Russian Mob.

The murder of a soldier stateside leads Jordan and Woody to a soldier who died in Iraq. Nigel is on the track of an old kidnapping, and Macy's daughter is dating someone he deems unsuitable.

A man asks Jordan to help find a friend who's in danger; an old friend of Macy's asks him to oversee the details concerning her husband's death.

Jordan helps Woody with the case of a woman who is into sexual sadism. Bug has to see the shrink after he accuses the parents of an autistic boy of murder. Garrett is seeing his ex-wife. Lily goes on holiday to see her brother on Mexico.

Lily tries to be supportive to a mother who has lost her son through aids from an infected tattoo needle, but Lily's tattoos cause the mother to shut down. Jordan meets with Dr. Stiles to discuss her past relationship with Tom Crane, whose estranged wife has been found dead. Macy and D.A. Wolcott are called to examine the body of Roland Winton, a prisoner who was executed on death row. His parents believe his execution was cruel and want it investigated.

A missing woman's body washes up in the ocean after a decade. Meanwhile, Dr. Winslow's estranged wife ends up in the morgue after a fatal drug overdose.