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A team of exceptional forensic pathologists and scientists investigate heinous crimes and use their skills to catch the people responsible.

Scotland Yard Commander Adam Dalgliesh has been on leave following the death on duty of a member of his team, DS Sarah Hillier. His superiors order him back to work to investigate the murder of the Director of the Steen Clinic, which specializes in psychiatric cases. Dalgliesh and his team can't quite figure out why they've been assigned to what seems to be a straightforward murder case but it's clear that his superiors want him to get in and out as quickly as possible. There is any number of possible suspects and as Dalgliesh is fond to say, the motive for murder is inevitably greed or love.

In a world overtaken by eternal darkness, the buttoned down entomologist abandons his phantoms to embrace the unknown. Oscar is a conservator at the Natural Science Museum, and spends most of his days surrounded by bugs. When Oscar isn't tending to the tiny specimens that line his home and workplace, he can frequently be found reflecting on his childhood traumas in the psychiatrist's office. One day, Oscar returns home from work to find an African woman from the museum lying in his bed.

A bald math teacher named Baldi Baldimore tries to get the new student to answer a question only the old students know and if they don't know, Baldi Baldimore will slap rulers until they get the student and it ends.

Mars suffers daily and never has a chance. While he is in a strip bar he falls in love with the Russian Sophia, whose son Sasha is being held by the Mafia.

A classical musician demands that his beautiful daughter and his young son follow in his footsteps despite their personal wishes.

When the body of a school principal, thought to be buried in Austria, is found under her own memorial in the school grounds, police detectives Andrew Dalziel and Peter Pascoe are called in to piece together the circumstances surrounding her untimely death.

When Mark James' decomposing body is found in an abandoned building, there is every indication that he was part of some occult ritual. An upside down cross was carved on his chest, his wrists were bound with ivy and he was strangled. All evidence points to his friend Sebastian Bird, a rich idler who allowed James to live in his house but who had also developed a expert knowledge of the occult before being sent down from Cambridge for having had an affair with a professor's wife. Sam Ryan's testy relationship with the police continues as she is having difficulty establishing a forensic link in the case and also for publicly criticizing the well-liked Police Surgeon, Dr. Richard Owen, for attending the crime scene without the proper protective clothing. Sam also has to deal with her rebellious nephew Ricky, who is constantly fighting with his mother and announces that he has left home to move in with her.

When a dozen people die in a cinema fire, Connor is in charge of the investigation. Sam Ryan is coming back to Cambridge.

Sam Ryan takes on a gangland murder case to help builder Brian McNally, whom she believes to be innocent.

The team is called out to Northern Ireland to investigate the bodies of two men killed by paramilitaries twenty years ago. For Sam, it is a case that is soon to turn personal.

Sam is shaken when she has to look into the death of a very dear friend, Dr. Annabelle Evans, a Cambridge professor. She was found in her home, badly beaten in what appears to be a botched burglary attempt. The police immediately focus on the husband as the likely killer but Sam suspects that an altercation at a local restaurant during the May Ball, where a waiter spilled wine on Annabelle and was fired on the spot, may provide another suspect. Sam is also intrigued by the relationship some of her students may have had with Annabelle, particularly when she learns her friend may have had a lover. In her personal life, Sam has moved on. Her sister Wyn has relocated to Ireland and Peter Ross has also been transferred. She does however run into an old friend who also happens to be an acquaintance of her business partner Trevor.

In a suspected terrorist attack on a London hotel a government minister is killed. As Sam and the team investigate the case, old friends and government officials soon muddy the water.

Questions about a celebrated pathologist's accuracy in past cases leads to several exhumations; Sam Ryan is assigned to reexamine the remains. One particularly brutal murder conviction depends on the time of death being precise. Two crucial witnesses are found: one on her deathbed, anxious to get something off her chest, and the other dead behind a remodeled wall.

Boxer Kevin Sharma dies from blows received in the ring, but pathologist Sam Ryan determines that he has a brain injury dating from sometime after his last bout two months ago. One of the governors of the boxing board, retired police Superintendent Jack Reeve, is concerned that it will reflect badly on them. Reeve is also trying to cancel one-time trainer Terence Cross' license after he is the victim of a hit and run accident that leaves him a quadriplegic. A new Detective Superintendent, Peter Ross, is now in charge and Sam and he knew each other many years previously. Trevor finds himself alone after his wife leaves him. Sam and her sister Wyn bury their mother

The team investigates the derailment of a train caused by someone leaving Maj. Mark Wiltshire's Land Rover on the tracks. The army is suspected but Wiltshire was in the officers mess at the time. The team have yet to identify the 21st victim, or determine if that person was on the train or in the car. Working with a survivor's group, they try to re-create where everyone was seated just prior to the crash occurring. When one of the survivors commits suicide, the crash claims its 22nd victim.