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The Korean War M*A*S*H unit veteran operates as Chief Surgeon in a major city hospital with his colleagues.

An outdoorsman and a city-bred lawyer team up to fight crime in San Francisco.

The new acting board chairman tries to pressure Arnold Slocum into retirement only four months short of his pension.

A young man admitted to the hospital following an accident informs the staff that his name is "42" and that he is an alien who is stranded on Earth. While building a transmitter to contact his home planet, 42 befriends a sick and lonely woman.

There is plenty of excitement at the hospital for the opening of the day care center. However, the excitement is short-lived when a child is injured in a fall and it is found out that the day care director was once in a mental institution.

Trapper's busy hospital schedule becomes even more hectic when family problems crowd in. Melanie arrives to inform him the their daughter Kim is planning to drop out of school.

When an eight-month-old baby is brought to the hospital with respiratory problems, x-rays show that the child is a dwarf.

Jackpot convinces several of the staff to invest in a promising young boxer he is managing, but after the fighter kills his opponent in his first professional match he begins to suffer mysterious injuries that may keep him out of the ring permanently.

Trapper's contract is up for renewal, and a jealous surgeon is trying to discredit him and take over his position as Chief of Surgery.

Someone is killing terminally ill patients at San Francisco Memorial, and it appears to be an inside job. A young woman with chronic pain is learning how to deal with it, but maybe not soon enough.

The doctors of San Francisco Memorial find themselves under the glare of a productivity analyst whose desire to get more work from staff leads her to bring back a doctor suspended for operating unnecessarily.

A baby admitted to the hospital for a urinary tract infection turns out to be a hermaphrodite, sparking a battle between the parents over which sex it should be.

Trapper fears an epidemic after the leader of a research project becomes mysteriously ill.

There is a bomb somewhere in the hospital set to go off at midnight, the night of Trapper's 10th anniversary as chief of surgery. The bomb squad can't find it, and the man who planted it is dying from bullet wounds.

Seventeen-year-old Dr. Elliot Schweitzer is a new intern at SFMH. He takes his work very seriously, pushing himself to the limit. Trapper tries to help him remember that there is more to medicine than science and books.

A couple desperate for a child adopts a black-market baby, only to discover that the infant is addicted to heroin and has a heart condition. Stanley recruits Trapper and Gonzo to join him in a relay race against Bay General.

Riverside comes under fire after he takes over one of Gonzo's patients who happens to be dating his father and she ends up almost dying from an allergic reaction to fluorine.

A 74-year-old woman who is admitted with a blocked artery in her leg has another problem - she is hooked on prescription medications. When Trapper and Gonzo discover that her doctor is responsible, and treats all his patients the same way, they plot to drive him out of business.

A rumor that Trapper may be leaving SFM for a hospital in Boston has several other staff considering new positions. After 72 hours on duty and the loss of a patient, Stanley is displaying psychotic symptoms, and ends up in jail.

San Francisco Memorial Hospital is endeavouring to put into place a co-operative care program, due to Arnold Slocomb and the Board of Directors' budget cuts. Mrs Fitch and her niece, Liza, are the perfect candidates, if Mrs. Fitch would only accept Liza's help.

Gonzo and Trapper are unsure how to treat a college student who has gotten mysteriously sick while doing a research paper on satanic rituals.

A mentally disabled man who works at the hospital is able to make friends with a crotchety old hermit who is dying of cancer, but gets embarrassed and quits his job when he misinterprets Gloria's feelings for him.

When an employee from a local nuclear power plant is admitted to SFM with signs of radiation poisoning, Gonzo cannot understand why it appears that nothing is being done to protect other workers from exposure. Meanwhile, Riverside must contend with a very distrusting Gypsy.

Jackpot is put in charge of Emergency Services while Trapper, Gonzo and Stanley attend a medical conference in Mexico. South of the border, Trapper falls in love with another doctor, but they may have too much in common for the romance to last.

When Melanie's mother comes for a surprise visit, Trapper learns that Melanie has kept their divorce a secret from her for the last six years. Gonzo suggests that a doctor should work as a nurse for a week to get a better idea of the problems they are having, and he gets volunteered for the job.