Dissociated FMDV SAT2 Pentamer in complex with ultralong Fab117
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9g6v
Q-score: 0.501
Clarke JD, Duyvesteyn HME, Perez-Martin E, Latisenko U, Porta C, Humphreys KV, Hay AL, Ren J, Fry EE, van den Born E, Charleston B, Bonnet-Di Placido M, Owens RJ, Stuart DI, Hammond JA
J Gen Virol (2024) 105 [ DOI: doi:10.1099/jgv.0.002032 Pubmed: 39422666 ]
- Fab117 heavy chain (32 kDa, Protein from Bos taurus)
- Genome polyprotein (24 kDa, Protein from Foot-and-mouth disease virus SAT 2)
- Genome polyprotein (24 kDa, Protein from Foot-and-mouth disease virus SAT 2)
- Pentamer from foot and mouth disease virus serotype sat2 vlps (Complex from Foot-and-mouth disease virus SAT 2)
- Complex of pentamer from foot and mouth disease virus serotype sat2 vlps with fab117. (Complex from Bos taurus)
- Genome polyprotein (24 kDa, Protein from Foot-and-mouth disease virus SAT 2)
- Fab117 (Complex from Bos taurus)
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8oyt
Q-score: 0.161
Cornish K, Huo J, Jones L, Sharma P, Thrush JW, Abdelkarim S, Kipar A, Ramadurai S, Weckener M, Mikolajek H, Liu S, Buckle I, Bentley E, Kirby A, Han X, Laidlaw SM, Hill M, Eyssen L, Norman C, Le Bas A, Clarke J, James W, Stewart JP, Carroll M, Naismith JH, Owens RJ
Open Biol (2024) 14 pp. 230252-230252 [ DOI: doi:10.1098/rsob.230252 Pubmed: 38835241 ]
- H6 nanobody (14 kDa, Protein from Lama glama)
- Stabilised hexapro omicron ba.1 spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,fibritin (140 kDa, Protein from Tequatrovirus T4)
- Complex of stabilised hexapro omicron ba.1 spike trimer with three h6 nanobodies (Complex)
- H6 nanobody (Complex from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
TREK2 in OGNG/CHS detergent micelle with biparatopic inhibitory nanobody Nb6158
Rodstrom KEJ, Cloake A, Sormann J, Baronina A, Smith KHM, Pike ACW, Ang J, Proks P, Schewe M, Holland-Kaye I, Bushell SR, Elliott J, Pardon E, Baukrowitz T, Owens RJ, Newstead S, Steyaert J, Carpenter EP, Tucker SJ
Nat Commun (2024) 15 pp. 4173-4173 [ DOI: doi:10.1038/s41467-024-48536-2 Pubmed: 38755204 ]
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8oyu
Q-score: 0.145
Cornish K, Huo J, Jones L, Sharma P, Thrush JW, Abdelkarim S, Kipar A, Ramadurai S, Weckener M, Mikolajek H, Liu S, Buckle I, Bentley E, Kirby A, Han X, Laidlaw SM, Hill M, Eyssen L, Norman C, Le Bas A, Clarke J, James W, Stewart JP, Carroll M, Naismith JH, Owens RJ
Open Biol (2024) 14 pp. 230252-230252 [ Pubmed: 38835241 DOI: doi:10.1098/rsob.230252 ]
- H6 nanobody (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein,fibritin (139 kDa, Protein from Enterobacteria phage T4)
- Stabilised hexapro omicron ba.1 spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
- Complex of stabilised hexapro omicron ba.1 spike trimer with two h6 nanobodies (Complex)
- H6 nanobody (Complex from Lama glama)
Mycroft-West CJ, Abdelkarim S, Duyvesteyn HME, Gandhi NS, Skidmore MA, Owens RJ, Wu L
Nat Commun (2024) 15 pp. 1326-1326 [ Pubmed: 38351061 DOI: doi:10.1038/s41467-024-45419-4 ]
Mycroft-West CJ, Abdelkarim S, Duyvesteyn HME, Gandhi NS, Skidmore MA, Owens RJ, Wu L
Nat Commun (2024) 15 pp. 1326-1326 [ Pubmed: 38351061 DOI: doi:10.1038/s41467-024-45419-4 ]
Mycroft-West CJ, Abdelkarim S, Duyvesteyn HME, Gandhi NS, Skidmore MA, Owens RJ, Wu L
Nat Commun (2024) 15 pp. 1326-1326 [ Pubmed: 38351061 DOI: doi:10.1038/s41467-024-45419-4 ]
Mycroft-West CJ, Abdelkarim S, Duyvesteyn HME, Gandhi NS, Skidmore MA, Owens RJ, Wu L
Nat Commun (2024) 15 pp. 1326-1326 [ Pubmed: 38351061 DOI: doi:10.1038/s41467-024-45419-4 ]
- Human heparan sulfate n-deacetylase-n-sulfotransferase complex with nab13 (Complex from Homo sapiens)
- Nanobody nab13 - all ca rigid fit model derived from nanobody nab7 (Protein from Lama glama)
- N-deacetylase-n-sulfotransferase 1 (Protein from Homo sapiens)
- N-deacetylase-n-sulfotransferase 1 (Complex from Homo sapiens)
- Nanobody nab13 - all ca rigid fit model derived from nanobody nab7 (Complex from Lama glama)
Mycroft-West CJ, Abdelkarim S, Duyvesteyn HME, Gandhi NS, Skidmore MA, Owens RJ, Wu L
Nat Commun (2024) 15 pp. 1326-1326 [ Pubmed: 38351061 DOI: doi:10.1038/s41467-024-45419-4 ]
- Human heparan sulfate n-deacetylase-n-sulfotransferase complex with nab13 (Complex from Homo sapiens)
- Nanobody nab13 - all ca rigid fit model derived from nanobody nab7 (Protein from Lama glama)
- N-deacetylase-n-sulfotransferase 1 (Protein from Homo sapiens)
- N-deacetylase-n-sulfotransferase 1 (Complex from Homo sapiens)
- Nanobody nab13 - all ca rigid fit model derived from nanobody nab7 (Complex from Lama glama)
Mycroft-West CJ, Abdelkarim S, Duyvesteyn HME, Gandhi NS, Skidmore MA, Owens RJ, Wu L
Nat Commun (2024) 15 pp. 1326-1326 [ Pubmed: 38351061 DOI: doi:10.1038/s41467-024-45419-4 ]
- Human heparan sulfate n-deacetylase-n-sulfotransferase complex with nab13 (Complex from Homo sapiens)
- Nanobody nab13 - all ca rigid fit model derived from nanobody nab7 (Protein from Lama glama)
- N-deacetylase-n-sulfotransferase 1 (Protein from Homo sapiens)
- N-deacetylase-n-sulfotransferase 1 (Complex from Homo sapiens)
- Nanobody nab13 - all ca rigid fit model derived from nanobody nab7 (Complex from Lama glama)