Papers by Professor Cristian Delcea, PhD
Pharmacophore, 2023
The COVID-19 pandemic has had a significant effect on people with HIV because of restricted acces... more The COVID-19 pandemic has had a significant effect on people with HIV because of restricted access to treatment facilities. Oral health is crucial for preventing systemic problems, such as bacterial infections or septicemia. These are serious effects for immunocompromised individuals. Oral lesions are the initial clinical manifestations of HIV infection and act as dependable markers of immunosuppression. This highlights their crucial role in the early assessment, identification, and management of these individuals. This study examines the oral symptoms observed in 156 healthy, COVID-19, and HIV-infected individuals amid the COVID-19 pandemic.
The individuals recruited for this study were patients of the Constanța Clinical Hospital of Infectious Diseases, between April 2021 and October 2022 which delayed their visit to healthcare facilities because of restricted access during the pandemic. Two patients were COVID-19 positive, other 52 were diagnosed with HIV and receiving antiretroviral treatment, and 52 healthy individuals were recruited as the CONTROL group. The lesions were identified based on clinical examination and laboratory results. Oral lesions remain prevalent in HIV-infected individuals throughout the COVID-19 pandemic. They are significant clinical signs appearing early and affecting up to 74% of HIV-infected individuals (CD4+ T cells <1640uL). Oral health affects physical and emotional well-being by potentially compromising oral aesthetics and altering different functions of the mouth as well as reducing the quality of life for patients. It is essential to include oral in the medical care of HIV-positive patients.
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Arch Pharm Pract, 2023
The present paper approaches the issue of maladaptive cognitive schemes in juvenile delinquency f... more The present paper approaches the issue of maladaptive cognitive schemes in juvenile delinquency from a psychological and forensic perspective. We south to highlight the differences in terms of maladaptive cognitive schemas depending on the criminal record and gender. A sample of 104 female and male minor participants, aged between 15 and 17 years, was selected, taking into account their criminal history. The data was collected with the Young Cognitive Schema Questionnaire (YSQ-L3a). Significant differences were obtained between the minors with and without criminal records. The work entitled Psychiatric and Psychological Forensic Approach of Maladaptive Cognitive Schemas in Juvenile Delinquency combined the trans theory of cognitive, medico-legal, psychiatric, and psychological schemes in the description and conceptualization of juvenile delinquency. Based on the instrument for the evaluation of cognitive schemes, significant results were obtained that can support the hypothesis of the current research. There were obtained as well significant gender differences in terms of maladaptive cognitive schemas for juvenile delinquents.
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arhive, 2023
The present paper approaches the issue of maladaptive cognitive schemes in juvenile delinquency f... more The present paper approaches the issue of maladaptive cognitive schemes in juvenile delinquency from a psychological and forensic perspective. We south to highlight the differences in terms of maladaptive cognitive schemas depending on the criminal record and gender. A sample of 104 female and male minor participants, aged between 15 and 17 years, was selected, taking into account their criminal history. The data was collected with the Young Cognitive Schema Questionnaire (YSQ-L3a). Significant differences were obtained between the minors with and without criminal records. The work entitled Psychiatric and Psychological Forensic Approach of Maladaptive Cognitive Schemas in Juvenile Delinquency combined the trans theory of cognitive, medico-legal, psychiatric, and psychological schemes in the description and conceptualization of juvenile delinquency. Based on the instrument for the evaluation of cognitive schemes, significant results were obtained that can support the hypothesis of the current research. There were obtained as well significant gender differences in terms of maladaptive cognitive schemas for juvenile delinquents.
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Pharmacophore, 2023
In protecting the rights of children, the courts have an extremely important role, that of promot... more In protecting the rights of children, the courts have an extremely important role, that of promoting and guaranteeing these rights regarding personal identity, family life, protection against violence, and ensuring the realization of their rights. As practitioners of law and psychology, we highlighted the opportunity and necessity of relaunching the discussions between specialists: magistrates/judges and prosecutors, psychologists, in the context where the courts are an unknown and authoritarian environment for children, and the multidisciplinary approach would contribute to the realization of an act of justice appropriate to the needs of children and can be a premise that can lead the courts and prosecutors to adopt a new way of solving such cases. This article supports the importance of the psychological assessment in the decision of the magistrate, considering the best interest of the minor. From the children's perspective, the courts are unfamiliar and intimidating places, which is why it is necessary to collaborate between specialists: magistrates, psychologists, social workers, counselors, and medical personnel to contribute to the achievement of a specific, qualitative act of justice appropriate to the particularities of children.
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Pharmacophore, 2023
The last period has been full of special situations. Among these, a particular case that caught o... more The last period has been full of special situations. Among these, a particular case that caught our attention is that of a person who is involuntarily admitted to a psychiatric ward because of their pathology, is subsequently diagnosed positive with SARS-CoV-2, and is admitted, suffers a very unfavorable evolution that ends in death. It thus becomes a forensic necropsy case and is examined from this point of view as well. The duty to maintain the integrity, health, and care of the involuntarily committed person is not only the responsibility of health professionals, the judiciary, or the people in whose care they are placed. It is not just a matter that can be assigned as a job task to the staff, it is a duty that belongs to the state and the state system, as appreciated in other studies. Involuntary admission is only in psychiatric hospitals that have adequate conditions for specialist care under specific conditions.
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Pharmacophore, 2023
The present work aims to explore the predictive value of maladaptive cognitive schemes such as De... more The present work aims to explore the predictive value of maladaptive cognitive schemes such as Defectiveness Shame, Vulnerability to harm or illness, failure, dependence incompetence, social isolation, and enmeshment/ undeveloped self on suicidal ideation and behavior of adolescents in the context of the COVID 19 pandemic. During 2020 -2022, a sample of 58 teenagers, male (61%) and female (39%), with an educational level of at least 9 classes, was selected. Data were collected with the Young Cognitive Schema Questionnaire in its short form (YSQ-S3) and the Beck Scale for Suicidal Ideations (BSSI), respecting ethical aspects regarding data processing and research participation. A multiple linear regression model was performed. The results indicate significant effects of Defectiveness Shame (DS), Vulnerability to harm or illness (VH), and Dependence Incompetence (DI). The model did not demonstrate the predictive value of Failure, Enmeshment/Undeveloped Self, and Social Isolation. Further replications and expansion of the results are needed.
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Scientific Reports, 2024
Pancreatic cancer is one of the most aggressive forms of cancer, and treatment options are limite... more Pancreatic cancer is one of the most aggressive forms of cancer, and treatment options are limited. One therapeutic approach is to use nanoparticles to deliver the active agent directly to pancreatic cancer cells. Nanoparticles can be designed to specifically target cancer cells, minimizing damage
to healthy tissues. Silver nanoparticles have the unique ability to absorb light, especially in the near‐infrared (NIR) region. In this study, silver nanoparticles functionalized with IgG molecules
were synthesized and administered to pancreatic cancer cell lines. Subsequently, the cells were photo‐excited using a 2 W 808 nm laser and further examined in PANC‐1 pancreatic cancer cell lines. Flow cytometry and confocal microscopy combined with immunochemical staining were used to examine the interaction between photo‐excited silver nanoparticles and pancreatic cancer cells. The photothermal therapy based on IgG‐functionalized silver nanoparticles in pancreatic cancer induces dysfunction in the Golgi apparatus, leading to the activation of the caspase‐3 apoptotic pathway and ultimately resulting in cellular apoptosis. These findings suggest that our proposed IgG nanoparticle laser treatment could emerge as a novel approach for the therapy of pancreatic cancer.
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Archives of Pharmacy Practice , 2024
The present paper aims to highlight potential gender differences in paraphilic interest in women ... more The present paper aims to highlight potential gender differences in paraphilic interest in women and men. Thus, paraphilic interests such as sexual sadism, sexual masochism, fetishism, and urophilia were targeted. The study was started in the period between 2022-2023, during which a sample of 224 participants of woman and man was selected of which 108 men and 116 women aged between 18 and 48 years. The data were collected with the Questionnaire on paraphilic disorders by accessing the participation link or by scanning a QR code with mobile phones in compliance with the norms of ethics and deontology. The obtained results indicated the existence of significant gender differences in terms of paraphilic-type interests. Men showed a significantly higher interest in sexual interests such as sexual sadism and urophilia. By comparison, women presented significantly higher sexual interests than men in terms of masochistic interests. Regarding fetishist interest, no significant gender differences were identified.
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Pharmaceutics, 2024
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
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Romanian Journal of Legal Medicine
The work aims to capture the specific peculiarities of the profile of the violent criminal, addre... more The work aims to capture the specific peculiarities of the profile of the violent criminal, addressing the issue of assuming responsibility as well as the importance of maladaptive cognitive schemes in violent criminals. The research was conducted on 126 participants, subgrouped according to criminal history. Data were collected with the Young cognitive Schema Questionnaire in its short form (YSQ-S3) for the assessment of maladaptive cognitive schemas and the ROSENZWEIG Frustration Test for the assessment of attribution of responsibility. The results highlighted the links between maladaptive cognitive schemas and the assumption of responsibility, as well as the tendency of violent offenders to assign responsibility to external sources.
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International Journal of Advanced Studies in Sexology, 2023
Models and researches related to the Sexual Self-Concept from the 21st century are based on a fra... more Models and researches related to the Sexual Self-Concept from the 21st century are based on a framework
developed by Buzwell and Rosenthal (1996), with six defined dimensions subsequently developed. The
Sexual Self-Concept represents a complex construct situated on multiple levels, including all conceptions
and feelings individuals have regarding themselves as a sexual being (Rye, 2023). My scientific work
explores the components, the factors of the Sexual Self-Concept, their relationships with sexual functions,
and the interactions between these elements. The models I have analyzed and the research hypotheses I
have previously examined suggest that the Sexual Self-Concept has impacts on the sexual functions. The
dimensions of the Sexual Self-Concept consist of various magnitudes, and their effects are not entirely
clear; however, studies indicate relationships between these dimensions and their influence on sexual
functioning.
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International Journal of Advanced Studies in Sexology , 2023
International Journal of Advanced Studies in Sexology (IJASS) is a scholarly journal devoted to t... more International Journal of Advanced Studies in Sexology (IJASS) is a scholarly journal devoted to the publication of articles relevant to the variety of disciplines involved in the scientific study of sexuality.
International Journal of Advanced Studies in Sexology (IJASS) is designed to stimulate research and promote an interdisciplinary understanding of the diverse topics in contemporary sexual science.
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INTERNATIONAL JOURNAL OF ADVANCED STUDIES IN SEXOLOGY, 2023
International Journal of Advanced Studies in Sexology (IJASS) is a scholarly journal devoted to t... more International Journal of Advanced Studies in Sexology (IJASS) is a scholarly journal devoted to the publication of articles relevant to the variety of disciplines involved in the scientific study of sexuality.
International Journal of Advanced Studies in Sexology (IJASS) is designed to stimulate research and promote an interdisciplinary understanding of the diverse topics in contemporary sexual science.
International Journal of Advanced Studies in Sexology (IJASS) publishes empirical reports, brief reports, theoretical essays, review articles, methodological articles, commentaries, and letters to the editor from researchers and practitioners in the fields of psychology, sociology, education, psychiatry, communication, and allied health.
Peer Review Policy: All submitted manuscripts are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is double blind and submission is online via https://www.sexology.ro/jurnal/ Manuscripts.
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International Journal of Advanced Studies in Sexology, 2024
Introduction. Affectional expression plays an important role in the dyadic adjustment in couples.... more Introduction. Affectional expression plays an important role in the dyadic adjustment in couples. It meas- ures the individual's satisfaction towards emotionality and sexuality expression in the relationship (1). This study aims to analyse the association between strain and affectional expression.
Material and Method. We selected 30 patients who declared themselves strained for the experimental group and 30 patients who declared not to be strained for the control group. We analysed the association between strain and agreement on sex relations and also the association between strain and feeling too tired for sex. Microsoft Excel and MedCalc were used for statistics
Results. The statistical analysis showed that subjects who declared themselves strained at the moment of evaluation had 14,5 more times disagreements with their partner regarding sex relations [OR=14,5, 95% CI (1,7177-122,4), P=0,0140]. Even though strained subjects were 1,96 times more tired for sex than subjects who did not consider themselves strained at the moment, the value did not reach statistical sig- nificance [OR=1,96, 95% CI (0,7023-5,4788), P=0,1986].
Conclusion. The affectional expression is being disturbed by the current state of strain, especially the cou- ples' agreement on intimate relations. In order to avoid separation and divorce, there is need of psycho- therapy, support and campaigns targeting strain, anxiety, depression, work-life balance and importance of sleep.
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Archives of Pharmacy Practice, 2024
Our research aimed to identify the risk factors that may contribute to postpartum depression (PPD... more Our research aimed to identify the risk factors that may contribute to postpartum depression (PPD) in the immediate postpartum period. The study was conducted at the University Emergency County Hospital Constanta, Romania, between 2019 and 2021. We included 904 women on the 2nd day of the postpartum period, divided into 2 groups: women with PPD (n=236) and control (women without PPD, n=668). Demographic characteristics and clinical information (i.e., women’s age, urban or rural areas, level of education, Rh blood group, chronic diseases, mode of delivery, women’s parity, and the number of abortions) were assessed. The prevalence of PPD found was 26.1%. Our findings suggest that only the women’s age and level of education were significantly associated with PPD (p=0.05 and p=0.002), being appraised as risk factors in PPD. Our study shows that early detection of PPD represents an important task for its prevention and women should be counseled in order to reduce negative child follow-up.
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Arch Pharm Pract, 2023
Pregnancy profoundly affects several aspects of a woman's life in today's society. Mental and phy... more Pregnancy profoundly affects several aspects of a woman's life in today's society. Mental and physical health have different incidences among pregnant women, and they also have a higher risk for certain psychological conditions. Starting from the group's psychological profiler and clinical psychologist, we chose a set of questioners and analyzed a group of pregnant women enrolled in the pregnancy follow-up program by their family doctor/G.P. Starting from the test-retest method, we analyzed pregnancy from several psychological perspectives (depression, anxiety, and self-esteem) and set out to determine these fluctuations by trimester of pregnancy. We chose the test and retest method to establish the initial level of depression, anxiety, and self-esteem and applied the questionnaires in each trimester, trying to apply them in the midweek (+/- 1 week) for each participant. All tests and questions indicated statistically significant increases of a worrying magnitude. An immediate priority of the scientific community should be collecting high-quality data on the mental health effects of the COVID-19 pandemic across the whole population and especially vulnerable groups such as pregnant women who were presented in this study.
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Archives of Pharmacy Practice, 2023
The present work addresses the controversial issue of incest by men. We sought to highlight that ... more The present work addresses the controversial issue of incest by men. We sought to highlight that the incestuous tendency in men becomes a sexual preference that isn’t determined directly by the existence of borderline or other personality traits or early maladaptive cognitive schemas. A sample of 48 males with confirmed incestuous tendencies was selected. 49% of them showed borderline personality traits and abandonment maladaptive cognitive schemas, their median age being m=38.17 and SD ±9.24 and the mean educational level, m= 13.11 and SD ±1.71. Data was collected with the Millon Multiaxial Clinical Inventory-III, the Young Cognitive Schema Questionnaire (YSQ-L3a), and the Paraphilic Disorders Questionnaire (PDQ). Significant correlations were obtained between borderline traits and the abandonment cognitive schema, the two factors interfering in most cases. A relevant association between incestuous tendencies and borderline traits was identified, yet without connections to the cognitive schema of abandonment. The factor analysis did not reveal the predictive potential of borderline traits, of the abandonment cognitive schema, or the interference of the two factors. Incestuous inclination in men doesn’t always result from personality or paraphilic disorders, but from sexual interests that are atypical for one’s species.
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healthcare, 2023
Road traffic accidents can have profound psychological impacts on the individuals involved, encom... more Road traffic accidents can have profound psychological impacts on the individuals involved, encompassing both negative distress and positive growth. This study, guided by the conservation of resources (COR) theory, investigates the intricate relationship between posttraumatic growth (PTG), maladaptive cognitive schemas, and psychological distress in individuals involved in road traffic accidents. PTG reflects an individual’s ability to derive positive changes from adversity, while maladaptive schemas represent negative cognitive patterns. Using a 122 sample of individuals involved in road traffic accidents, we examined direct and indirect effects within this complex network. Our findings reveal significant direct effects of PTG on psychological distress (β = 0.101, p = 0.02). Particularly noteworthy are the indirect effects mediated by cognitive schemas, emphasizing the role of impaired autonomy and perceived performance deficiencies (β = 0.102, p = 0.05). This suggests that individuals involved in road traffic accidents experiencing higher PTG levels may indirectly experience greater psychological distress through these maladaptive cognitive schemas. This study not only advances our understanding of the psychological consequences of road traffic accidents but also aligns with self-determination theory, emphasizing autonomy and competence as fundamental needs. Individuals involved in road traffic accidents may undergo profound shifts in perspective following the trauma, which our results support. Recognizing the nuanced relationship between PTG, maladaptive cognitive schemas, and psychological distress is crucial for tailoring interventions and support systems for individuals involved in traffic accidents. As PTG can coexist with distress, interventions should foster adaptive growth while addressing maladaptive schemas to promote resilience in the face of traumatic events.
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Pharmacophore, 2023
Psychological distress represents a complex and pervasive concern impacting individuals globally,... more Psychological distress represents a complex and pervasive concern impacting individuals globally, characterized by a wide spectrum of emotional, cognitive, and physiological experiences. This multifaceted phenomenon is frequently intertwined with the presence of maladaptive cognitive schemas and heightened levels of anxiety, both recognized as contributing factors. Accurate prediction of psychological distress is of paramount significance for clinicians, researchers, and healthcare practitioners as it can drive early interventions, and personalized treatment plans, and optimize resource allocation. This research delves into the predictive capabilities of maladaptive cognitive schemas and anxiety in the context of psychological distress, employing the Random Forest Regression (RFR) algorithm. The RFR algorithm, a powerful ensemble learning method, offers the potential to comprehensively explore the intricate interplay of variables and predictors, enhancing the precision of psychological distress prediction. By harnessing the capabilities of this advanced algorithm, we seek to provide a more robust framework for understanding, assessing, and addressing psychological distress. This research aspires to illuminate the predictive potential of maladaptive cognitive schemas and anxiety, thereby contributing to the development of more effective early interventions and personalized treatment strategies. Ultimately, this study holds the promise of significantly improving our capacity to predict and intervene in cases of psychological distress, ultimately enhancing the well-being of individuals and the efficiency of healthcare delivery.
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Annals of Dental Specialty, 2023
The COVID-19 pandemic has posed unprecedented challenges to individuals worldwide, demanding the ... more The COVID-19 pandemic has posed unprecedented challenges to individuals worldwide, demanding the rapid development and utilization of coping mechanisms to navigate the recurring waves of uncertainty and disruption. Coping mechanisms are mediated by personality traits, cognitive schemes and developed perceptions. They are activated in states of stress, danger or events such as the COVID-19 period. Our study employing a network analysis approach sheds light on the coping mechanisms utilized during the recurring periods of the COVID era among a convenience sampling of 403 respondents in Romania. The findings highlight that substance use emerges as the most destabilizing factor within the pandemic resilience network, while the use of instrumental support exhibits the highest expected influence, offering valuable insights into the adaptive and maladaptive strategies that shape the Romanian population's resilience during these challenging times.They highlight the complex interplay of coping strategies and the need for tailored interventions that consider the influential positions and susceptibilities of specific coping mechanisms within the context of recurring COVID-19 waves.
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Papers by Professor Cristian Delcea, PhD
The individuals recruited for this study were patients of the Constanța Clinical Hospital of Infectious Diseases, between April 2021 and October 2022 which delayed their visit to healthcare facilities because of restricted access during the pandemic. Two patients were COVID-19 positive, other 52 were diagnosed with HIV and receiving antiretroviral treatment, and 52 healthy individuals were recruited as the CONTROL group. The lesions were identified based on clinical examination and laboratory results. Oral lesions remain prevalent in HIV-infected individuals throughout the COVID-19 pandemic. They are significant clinical signs appearing early and affecting up to 74% of HIV-infected individuals (CD4+ T cells <1640uL). Oral health affects physical and emotional well-being by potentially compromising oral aesthetics and altering different functions of the mouth as well as reducing the quality of life for patients. It is essential to include oral in the medical care of HIV-positive patients.
to healthy tissues. Silver nanoparticles have the unique ability to absorb light, especially in the near‐infrared (NIR) region. In this study, silver nanoparticles functionalized with IgG molecules
were synthesized and administered to pancreatic cancer cell lines. Subsequently, the cells were photo‐excited using a 2 W 808 nm laser and further examined in PANC‐1 pancreatic cancer cell lines. Flow cytometry and confocal microscopy combined with immunochemical staining were used to examine the interaction between photo‐excited silver nanoparticles and pancreatic cancer cells. The photothermal therapy based on IgG‐functionalized silver nanoparticles in pancreatic cancer induces dysfunction in the Golgi apparatus, leading to the activation of the caspase‐3 apoptotic pathway and ultimately resulting in cellular apoptosis. These findings suggest that our proposed IgG nanoparticle laser treatment could emerge as a novel approach for the therapy of pancreatic cancer.
developed by Buzwell and Rosenthal (1996), with six defined dimensions subsequently developed. The
Sexual Self-Concept represents a complex construct situated on multiple levels, including all conceptions
and feelings individuals have regarding themselves as a sexual being (Rye, 2023). My scientific work
explores the components, the factors of the Sexual Self-Concept, their relationships with sexual functions,
and the interactions between these elements. The models I have analyzed and the research hypotheses I
have previously examined suggest that the Sexual Self-Concept has impacts on the sexual functions. The
dimensions of the Sexual Self-Concept consist of various magnitudes, and their effects are not entirely
clear; however, studies indicate relationships between these dimensions and their influence on sexual
functioning.
International Journal of Advanced Studies in Sexology (IJASS) is designed to stimulate research and promote an interdisciplinary understanding of the diverse topics in contemporary sexual science.
International Journal of Advanced Studies in Sexology (IJASS) is designed to stimulate research and promote an interdisciplinary understanding of the diverse topics in contemporary sexual science.
International Journal of Advanced Studies in Sexology (IJASS) publishes empirical reports, brief reports, theoretical essays, review articles, methodological articles, commentaries, and letters to the editor from researchers and practitioners in the fields of psychology, sociology, education, psychiatry, communication, and allied health.
Peer Review Policy: All submitted manuscripts are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is double blind and submission is online via https://www.sexology.ro/jurnal/ Manuscripts.
Material and Method. We selected 30 patients who declared themselves strained for the experimental group and 30 patients who declared not to be strained for the control group. We analysed the association between strain and agreement on sex relations and also the association between strain and feeling too tired for sex. Microsoft Excel and MedCalc were used for statistics
Results. The statistical analysis showed that subjects who declared themselves strained at the moment of evaluation had 14,5 more times disagreements with their partner regarding sex relations [OR=14,5, 95% CI (1,7177-122,4), P=0,0140]. Even though strained subjects were 1,96 times more tired for sex than subjects who did not consider themselves strained at the moment, the value did not reach statistical sig- nificance [OR=1,96, 95% CI (0,7023-5,4788), P=0,1986].
Conclusion. The affectional expression is being disturbed by the current state of strain, especially the cou- ples' agreement on intimate relations. In order to avoid separation and divorce, there is need of psycho- therapy, support and campaigns targeting strain, anxiety, depression, work-life balance and importance of sleep.
The individuals recruited for this study were patients of the Constanța Clinical Hospital of Infectious Diseases, between April 2021 and October 2022 which delayed their visit to healthcare facilities because of restricted access during the pandemic. Two patients were COVID-19 positive, other 52 were diagnosed with HIV and receiving antiretroviral treatment, and 52 healthy individuals were recruited as the CONTROL group. The lesions were identified based on clinical examination and laboratory results. Oral lesions remain prevalent in HIV-infected individuals throughout the COVID-19 pandemic. They are significant clinical signs appearing early and affecting up to 74% of HIV-infected individuals (CD4+ T cells <1640uL). Oral health affects physical and emotional well-being by potentially compromising oral aesthetics and altering different functions of the mouth as well as reducing the quality of life for patients. It is essential to include oral in the medical care of HIV-positive patients.
to healthy tissues. Silver nanoparticles have the unique ability to absorb light, especially in the near‐infrared (NIR) region. In this study, silver nanoparticles functionalized with IgG molecules
were synthesized and administered to pancreatic cancer cell lines. Subsequently, the cells were photo‐excited using a 2 W 808 nm laser and further examined in PANC‐1 pancreatic cancer cell lines. Flow cytometry and confocal microscopy combined with immunochemical staining were used to examine the interaction between photo‐excited silver nanoparticles and pancreatic cancer cells. The photothermal therapy based on IgG‐functionalized silver nanoparticles in pancreatic cancer induces dysfunction in the Golgi apparatus, leading to the activation of the caspase‐3 apoptotic pathway and ultimately resulting in cellular apoptosis. These findings suggest that our proposed IgG nanoparticle laser treatment could emerge as a novel approach for the therapy of pancreatic cancer.
developed by Buzwell and Rosenthal (1996), with six defined dimensions subsequently developed. The
Sexual Self-Concept represents a complex construct situated on multiple levels, including all conceptions
and feelings individuals have regarding themselves as a sexual being (Rye, 2023). My scientific work
explores the components, the factors of the Sexual Self-Concept, their relationships with sexual functions,
and the interactions between these elements. The models I have analyzed and the research hypotheses I
have previously examined suggest that the Sexual Self-Concept has impacts on the sexual functions. The
dimensions of the Sexual Self-Concept consist of various magnitudes, and their effects are not entirely
clear; however, studies indicate relationships between these dimensions and their influence on sexual
functioning.
International Journal of Advanced Studies in Sexology (IJASS) is designed to stimulate research and promote an interdisciplinary understanding of the diverse topics in contemporary sexual science.
International Journal of Advanced Studies in Sexology (IJASS) is designed to stimulate research and promote an interdisciplinary understanding of the diverse topics in contemporary sexual science.
International Journal of Advanced Studies in Sexology (IJASS) publishes empirical reports, brief reports, theoretical essays, review articles, methodological articles, commentaries, and letters to the editor from researchers and practitioners in the fields of psychology, sociology, education, psychiatry, communication, and allied health.
Peer Review Policy: All submitted manuscripts are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is double blind and submission is online via https://www.sexology.ro/jurnal/ Manuscripts.
Material and Method. We selected 30 patients who declared themselves strained for the experimental group and 30 patients who declared not to be strained for the control group. We analysed the association between strain and agreement on sex relations and also the association between strain and feeling too tired for sex. Microsoft Excel and MedCalc were used for statistics
Results. The statistical analysis showed that subjects who declared themselves strained at the moment of evaluation had 14,5 more times disagreements with their partner regarding sex relations [OR=14,5, 95% CI (1,7177-122,4), P=0,0140]. Even though strained subjects were 1,96 times more tired for sex than subjects who did not consider themselves strained at the moment, the value did not reach statistical sig- nificance [OR=1,96, 95% CI (0,7023-5,4788), P=0,1986].
Conclusion. The affectional expression is being disturbed by the current state of strain, especially the cou- ples' agreement on intimate relations. In order to avoid separation and divorce, there is need of psycho- therapy, support and campaigns targeting strain, anxiety, depression, work-life balance and importance of sleep.
This monograph brings together 8 scientific articles and includes the research work of
young teams’ international researchers from Kosovo, the Netherlands, Israel, Romania, Serbia
and Hungary, who despite Covid-19 pandemic and the lockdowns they were in continued to
study and research diligently in the field of sexology.
Sex life during this period is clearly and obviously affected, but the way in which the bat
changed behavior, functionality and perception about and sex and sexuality you can find it
carefully reading this monograph whose main purpose is to answer the question: “how are we
having sex in a pandemic?” Paradoxically better, more, more intense, and different, as we like
in other words ... that is, sex caught the bat or vice versa... it remains to be seen.
Obviously, the appearance of this monograph is an exciting read, well documented and
using a Rigorous methodology conclusions and discussions show the high level of
professionalism of researchers who brought added value in this area of research during the
Covid-19 pandemic.
Professor Horea Vladi MATEI, MD, PhD
Iuliu Hațieganu University of Medicine and Pharmacy, Romania
Pentru a ajunge la aceste concluzii, cercetările din domeniul matematicii, economiei și a psihologiei sociale au fost o provocare pentru criminaliști, medici legiști și psihologi. Ca urmare a contribuțiilor științifice ale lui Herbert Alexander Simon [1], Milton Frienman [2], Gary Stanley Becker [3] și Daniel Kahneman [4], Robert J. Shiller [5], au fost elaborate două paradigme validate științific: una normativă și una descriptivă. S-a observat existența unor discrepanțe în conceptualizarea proceselor decizionale.
Teoria normativă face referire la potențialul computațional de reprezentare și calcul rațional a prelucrărilor informaționale, operate de decident, astfel încât orice decizie luată este reală și logică. Această teorie are formule de reprezentare și calcul/computațional pentru decizii în condiții de incertitudine / certitudine de tip multi-atribut în condiții de certitudine / incertitudine, pentru decizii în condiții de risc și de tip multi-stagiu sau pentru decizii de grup / sociale.
A doua paradigmă, denumită descriptivă sau rațional limitată, ia în calcul deficitul resurselor de timp și date cognitive datorită prelucrării volumului mare de lucru a decidentului astfel încât individul nu se va raporta la cost-beneficiu sau la varianta optimă, ci mai degrabă la formula de calcul satisfăcătoare. Aceasta înseamnă că satisfacerea este mediată de percepții subiective de tip cognitiv sau afectiv și/sau emoțional.
Teoriile de mai sus au contribuit major la descrierea stilurilor decizionale umane, însă sunt insuficiente în abordarea procesului decizional în actul de omor. Majoritatea studiilor pe luarea deciziilor au fost validate pe comportamentul consumatorului, pe decizii în condiții non-clinice și pe optimizarea performanțelor profesionale în domeniul bancar, industrial și alte domenii asociate. Există foarte puține studii realizate din perspectiva raționalității limitate în cazul omorului cu premeditare, terorism și tâlhărie, iar studiile existente au la bază variabile precum factorul visceral, schemele cognitive și emoționale dezadaptative ca predictori ai crimei. Există și multe critici aduse din cauza studiilor experimentale reduse [6].
Comparativ cu studiile menționate mai sus, cercetările pe tulburările de personalitate sau pe trăsăturile psihopatologice de personalitate aduc noi dezvăluiri teoretico-experimentale cu privire la decidentul condamnat pentru crimă. Aceste abordări au o mai bună conceptualizare clinică și o bună descriere a decidentului în actul de omor. De fapt, schemele cognitive dezadaptative timpurii pot duce la dezvoltarea unor trăsături psihopatologice de personalitate, iar aceste trăsături mediază o decizie care conduce la criminalitate. Spre exemplu, domeniul Separare și Respingere cu cele cinci scheme dezadaptative timpurii (abandon/instabilitate, neîncredere/abuz, deprivare emoțională, deficiență/rușine, izolare socială/înstrăinare), descrise și validate științific de Jeffrey R. Young [7], cu privire la tulburările de personalitate, aduce o nouă abordare, mult mai predictibilă și robustă în creionarea decidentului.
O altă abordare cu privire la personalitatea decidentului în actul de omor este cuprinsă în cercetarea lui H. J. Eysenck [8], fiind realizată din perspectiva factorilor care pot defini o dimensiune psihopatologică a decidentului în actul de omor. Spre exemplu, autorii paradigmei au concluzionat că un cumul ridicat de factori nevrotism-psihotism poate duce la crimă; scoruri scăzute la extraversie și ridicate la psihotism pot dezvolta o trăsătură de personalitate spre adicție și criminalitate. Iar aceste pattern-uri de personalitate psihopatologică pot media o decizie care duce la omor sau un stil de viață antisocial.
on all aspects of legal medicine. The medical principles of care and forensic assessment of
living individuals, whether adult or child, in contact with the judicial system are examined and
the Journal has a broad international perspective.
Topics covered in e-book include the following, particularly with relevance to the clinical
setting: forensic medicine and psychiatry, including child abuse and neglect, interpersonal
violence, elder abuse, domestic violence, sexual violence, suicidal behaviors, care in custody,
restraint injuries, torture, and human rights; forensic pathology, death investigation and causes
of death, including death in custody and suicide; forensic science, including the forensic aspects
of toxicology, anthropology, and odontology.
Professor Horea Vladi MATEI, MD, PhD
Iuliu Hațieganu University of Medicine and Pharmacy, Romania
International Journal of Advanced Studies in Sexology (IJASS) is designed to stimulate research and promote an interdisciplinary understanding of the diverse topics in contemporary sexual science.
International Journal of Advanced Studies in Sexology (IJASS) publishes empirical reports, brief reports, theoretical essays, review articles, methodological articles, commentaries, and letters to the editor from researchers and practitioners in the fields of psychology, sociology, education, psychiatry, communication, and allied health.
Peer Review Policy: All submitted manuscripts are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is double blind and submission is online via sexology.ro Manuscripts.
The journal is launched from 2019, appears biannually (January June / July December). The journal is published by the Sexology Institute of Romania and has ISSN 2668-7194, ISSN 2668-7194 (online).
International Database Indexing: Web of Science Core Collection (Emerging Sources Citation Index).
IS Team
20 adolescents, aged between 16-17 years, all pupils of a vocational high school. The surveyed adolescents were classified in one of three categories: low stress, moderate stress and high stress. Analysing the data on coping strategies, we found that active coping strategies represent a percentage of 37.70% of their choices, passive coping strategies 38.8% and dysfunctional strategies 23.50% The correlation analysis between the perceived stress variable and the coping strategies used highlights the presence of a strong positive association between stress level and behavioural passivity coping strategy, a significant correlation with the coping strategy of mental passivity, but also a strongly negative correlation of the stress level with the coping planning strategy. The results indicated that almost half of the adolescents evaluated have a high level of stress. Girls scored higher on the stress perception scale than boys.
Conference of Forensic Medicine, the 4th edition, during September 30-October 3, 2021 in
Cluj-Napoca Romania, which continues the tradition of the events dedicated to forensics and
legal-medicine as the main subject linking specialists from different domains and from
different countries.
The scope established for this event that of transdisciplinarity is obvious, especially in the
paper sessions dedicated to: forensics, legal sciences and psychology. Papers presented in
these sessions were selected, analysed and reviewed by the conference Scientific Committee,
going through a blind peer-review process in order to be introduced in The Proceedings of the
International Conference of Forensic Medicine from Cluj-Napoca, 4th edition.
This volume thus collects some studies which were presented during the conference and
which were considered to be the most relevant for the scope of this event, that of bringing
together researchers and practitioners in the fields of forensics, medicine, law, penitentiary,
psychology, legal, etc. to add knowledge to our community, supporting the forensics domain.
The scientific committee of this conference is thus responsible for the review of materials
included in the proceedings volume and gathers specialists from different countries, among
which the following can be mentioned:
This event continues an already established tradition for the field of forensic medicine in
Romania and desires to become a landmark in the forensics domain, offering specialists,
researchers and practitioners to share knowledge and to be up to date to everything that is
going on in this domain.
Associate Professor Costel Vasile SISERMAN MD, PhD, MSc
Associate Professor Cristian DELCEA PhD