Disponible en: http://redalyc.uaemex.mx/src/inicio/ArtPdfRed.jsp?iCve=85015147009 ... Redalyc Sis... more Disponible en: http://redalyc.uaemex.mx/src/inicio/ArtPdfRed.jsp?iCve=85015147009 ... Redalyc Sistema de Información Científica Red de Revistas Científicas de América Latina, el Caribe, España y Portugal ... Mendonça Mezzomo, Luis André; Silveira, Maurício; Corrêa Batista, ...
To evaluate new bone formation in calvarial critical size defects (CSD) under dense polytetrafluo... more To evaluate new bone formation in calvarial critical size defects (CSD) under dense polytetrafluoroethylene (d-PTFE), microporous membranes for guided bone regeneration (GBR) in healthy, osteoporotic and osteoporotic treated with zoledronic acid (ZA) rats. Forty-eight, female, 6-month old Wistar rats were included in the study. Osteoporosis was induced by ovariectomy (OVX) and calcium-deficient diet in 32 rats. Sixteen OVX rats were treated with a single dose of Zolendronic Acid (ZA) (OZ), while 16 OVX rats received no treatment (O). The remaining 16 rats were sham-operated and used as healthy controls (C). At 6 weeks following osteoporosis induction, two 5 mm CSD were created in the parietal bones and one of them was treated with a double d-PTFE membrane. The healing periods were 30 and 60 days. New bone formation (NB) was assessed by qualitative and quantitative histological analysis. After 30 days of healing, NB (mean% (95% CI)) was 78.9% (21), 93.1% (9.3) and 84.2% (26.9) in the...
Serum biomarkers could be helpful to characterize head and neck squamous cell carcinoma (HNSCC). ... more Serum biomarkers could be helpful to characterize head and neck squamous cell carcinoma (HNSCC). Thus, the purpose of this systematic review and meta-analysis was to determine the diagnostic capability of serum biomarkers in the assessment of HNSCC patients. Studies were gathered by searching LILACS, PubMed, Science Direct, Scopus and Web of Science up to April 10th, 2015. Studies that focused on serum biomarkers in the diagnosis of HNSCC compared with controls were considered. Sixty-five studies were identified, and the sample size included 9098 subjects. Combined biomarkers demonstrated improved accuracy than those tested individually. Therefore, 12.8% of single and 34.3% of combined indicated that serum biomarkers discriminate patients with HNSCC from controls. The combined biomarkers with better diagnostic capability included Epidermal growth factor receptor (EGFR)+Cyclin D1 and squamous cell cancer-associated antigen (SCCA)+EGFR+Cyclin D1. Beta2-microglobin may also be a promising single biomarker for future studies. Serum biomarkers can be potentially useful in the diagnosis of HNSCC. However, further research is required to validate these biomarkers.
Endodontic diagnosis depends on accurate radiographic examination. Assessment of the location and... more Endodontic diagnosis depends on accurate radiographic examination. Assessment of the location and extent of apical periodontitis (AP) can influence treatment planning and subsequent treatment outcomes. Therefore, this systematic review and meta-analysis assessed the diagnostic accuracy of conventional radiography and cone-beam computed tomographic (CBCT) imaging on the discrimination of AP from no lesion. Eight electronic databases with no language or time limitations were searched. Articles in which the primary objective was to evaluate the accuracy (sensitivity and specificity) of any type of radiographic technique to assess AP in humans were selected. The gold standard was the histologic examination for actual AP (in vivo) or in situ visualization of bone defects for induced artificial AP (in vitro). Accuracy measurements described in the studies were transformed to construct receiver operating characteristic curves and forest plots with the aid of Review Manager v.5.2 (The Nordi...
CONTEXT: Symptoms associated with the primary tooth eruption have been extensively studied but it... more CONTEXT: Symptoms associated with the primary tooth eruption have been extensively studied but it is still controversial. OBJECTIVE: To assess the occurrence of local and systemic signs and symptoms during primary tooth eruption. DATA SOURCES: Latin American and Caribbean Health Sciences, PubMed, ProQuest, Scopus, and Web of Science were searched. A partial gray literature search was taken by using Google Scholar and the reference lists of the included studies were scanned. STUDY SELECTION: Observational studies assessing the association of eruption of primary teeth with local and systemic signs and symptoms in children aged 0 to 36 months were included. DATA EXTRACTION: Two authors independently collected the information from the selected articles. Information was crosschecked and confirmed for its accuracy. RESULTS: A total of 1179 articles were identified, and after a 2-phase selection, 16 studies were included. Overall prevalence of signs and symptoms occurring during primary to...
Patients undergoing ophthalmic surgery are usually elderly and, due to systemic disease, may be o... more Patients undergoing ophthalmic surgery are usually elderly and, due to systemic disease, may be on long-term therapy, such as antithrombotic agents. Rates of hemorrhagic complications associated with invasive procedures may be increased by the use of anticoagulants and antiplatelet agents. To compare the incidence of hemorrhagic complications in patients undergoing needle-based ophthalmic regional anesthesia between patients on antithrombotic therapy and those not on such therapy. A systematic review was conducted by two independent reviewers based on searches of Cochrane, LILACS, PubMed, Scopus, Web of Science, and the "gray" literature (Google Scholar). The end search date was May 8, 2015, across all databases. Five studies met the eligibility criteria. In three studies, individual risk of bias was low, and in two of them, moderate. In all studies, no differences regarding mild to moderate incidence of hemorrhagic complications were found between patients using antithrom...
Objective: To evaluate the effect of various materials and techniques for alveolar ridge preserva... more Objective: To evaluate the effect of various materials and techniques for alveolar ridge preservation (ARP) following tooth extraction on ridge dimensions and histological healing characteristics. Methods: A systematic electronic search in MEDLINE, EMBASE, CENTRAL and LILACS and a hand search in selected dental journals were performed. Randomised controlled trials, controlled clinical trials and prospective cohort studies with unassisted socket healing as control, were eligible. The screening and data abstraction were performed independently and in duplicate. Results: The screening of 6,216 titles, 157 abstracts and 45 full text articles identified 13 eligible studies. Seven papers reported alveolar ridge dimensional changes based on clinical parameters and two papers on CT scans. Histological analysis was presented in 10/13 studies. Mean change in clinical alveolar ridge width varied between -1.20.9mm and -3.52.7mm in ARP groups, and between -2.62.3mm and -4.60.3mm in the controls....
Disponible en: http://redalyc.uaemex.mx/src/inicio/ArtPdfRed.jsp?iCve=85015147009 ... Redalyc Sis... more Disponible en: http://redalyc.uaemex.mx/src/inicio/ArtPdfRed.jsp?iCve=85015147009 ... Redalyc Sistema de Información Científica Red de Revistas Científicas de América Latina, el Caribe, España y Portugal ... Mendonça Mezzomo, Luis André; Silveira, Maurício; Corrêa Batista, ...
To evaluate new bone formation in calvarial critical size defects (CSD) under dense polytetrafluo... more To evaluate new bone formation in calvarial critical size defects (CSD) under dense polytetrafluoroethylene (d-PTFE), microporous membranes for guided bone regeneration (GBR) in healthy, osteoporotic and osteoporotic treated with zoledronic acid (ZA) rats. Forty-eight, female, 6-month old Wistar rats were included in the study. Osteoporosis was induced by ovariectomy (OVX) and calcium-deficient diet in 32 rats. Sixteen OVX rats were treated with a single dose of Zolendronic Acid (ZA) (OZ), while 16 OVX rats received no treatment (O). The remaining 16 rats were sham-operated and used as healthy controls (C). At 6 weeks following osteoporosis induction, two 5 mm CSD were created in the parietal bones and one of them was treated with a double d-PTFE membrane. The healing periods were 30 and 60 days. New bone formation (NB) was assessed by qualitative and quantitative histological analysis. After 30 days of healing, NB (mean% (95% CI)) was 78.9% (21), 93.1% (9.3) and 84.2% (26.9) in the...
Serum biomarkers could be helpful to characterize head and neck squamous cell carcinoma (HNSCC). ... more Serum biomarkers could be helpful to characterize head and neck squamous cell carcinoma (HNSCC). Thus, the purpose of this systematic review and meta-analysis was to determine the diagnostic capability of serum biomarkers in the assessment of HNSCC patients. Studies were gathered by searching LILACS, PubMed, Science Direct, Scopus and Web of Science up to April 10th, 2015. Studies that focused on serum biomarkers in the diagnosis of HNSCC compared with controls were considered. Sixty-five studies were identified, and the sample size included 9098 subjects. Combined biomarkers demonstrated improved accuracy than those tested individually. Therefore, 12.8% of single and 34.3% of combined indicated that serum biomarkers discriminate patients with HNSCC from controls. The combined biomarkers with better diagnostic capability included Epidermal growth factor receptor (EGFR)+Cyclin D1 and squamous cell cancer-associated antigen (SCCA)+EGFR+Cyclin D1. Beta2-microglobin may also be a promising single biomarker for future studies. Serum biomarkers can be potentially useful in the diagnosis of HNSCC. However, further research is required to validate these biomarkers.
Endodontic diagnosis depends on accurate radiographic examination. Assessment of the location and... more Endodontic diagnosis depends on accurate radiographic examination. Assessment of the location and extent of apical periodontitis (AP) can influence treatment planning and subsequent treatment outcomes. Therefore, this systematic review and meta-analysis assessed the diagnostic accuracy of conventional radiography and cone-beam computed tomographic (CBCT) imaging on the discrimination of AP from no lesion. Eight electronic databases with no language or time limitations were searched. Articles in which the primary objective was to evaluate the accuracy (sensitivity and specificity) of any type of radiographic technique to assess AP in humans were selected. The gold standard was the histologic examination for actual AP (in vivo) or in situ visualization of bone defects for induced artificial AP (in vitro). Accuracy measurements described in the studies were transformed to construct receiver operating characteristic curves and forest plots with the aid of Review Manager v.5.2 (The Nordi...
CONTEXT: Symptoms associated with the primary tooth eruption have been extensively studied but it... more CONTEXT: Symptoms associated with the primary tooth eruption have been extensively studied but it is still controversial. OBJECTIVE: To assess the occurrence of local and systemic signs and symptoms during primary tooth eruption. DATA SOURCES: Latin American and Caribbean Health Sciences, PubMed, ProQuest, Scopus, and Web of Science were searched. A partial gray literature search was taken by using Google Scholar and the reference lists of the included studies were scanned. STUDY SELECTION: Observational studies assessing the association of eruption of primary teeth with local and systemic signs and symptoms in children aged 0 to 36 months were included. DATA EXTRACTION: Two authors independently collected the information from the selected articles. Information was crosschecked and confirmed for its accuracy. RESULTS: A total of 1179 articles were identified, and after a 2-phase selection, 16 studies were included. Overall prevalence of signs and symptoms occurring during primary to...
Patients undergoing ophthalmic surgery are usually elderly and, due to systemic disease, may be o... more Patients undergoing ophthalmic surgery are usually elderly and, due to systemic disease, may be on long-term therapy, such as antithrombotic agents. Rates of hemorrhagic complications associated with invasive procedures may be increased by the use of anticoagulants and antiplatelet agents. To compare the incidence of hemorrhagic complications in patients undergoing needle-based ophthalmic regional anesthesia between patients on antithrombotic therapy and those not on such therapy. A systematic review was conducted by two independent reviewers based on searches of Cochrane, LILACS, PubMed, Scopus, Web of Science, and the "gray" literature (Google Scholar). The end search date was May 8, 2015, across all databases. Five studies met the eligibility criteria. In three studies, individual risk of bias was low, and in two of them, moderate. In all studies, no differences regarding mild to moderate incidence of hemorrhagic complications were found between patients using antithrom...
Objective: To evaluate the effect of various materials and techniques for alveolar ridge preserva... more Objective: To evaluate the effect of various materials and techniques for alveolar ridge preservation (ARP) following tooth extraction on ridge dimensions and histological healing characteristics. Methods: A systematic electronic search in MEDLINE, EMBASE, CENTRAL and LILACS and a hand search in selected dental journals were performed. Randomised controlled trials, controlled clinical trials and prospective cohort studies with unassisted socket healing as control, were eligible. The screening and data abstraction were performed independently and in duplicate. Results: The screening of 6,216 titles, 157 abstracts and 45 full text articles identified 13 eligible studies. Seven papers reported alveolar ridge dimensional changes based on clinical parameters and two papers on CT scans. Histological analysis was presented in 10/13 studies. Mean change in clinical alveolar ridge width varied between -1.20.9mm and -3.52.7mm in ARP groups, and between -2.62.3mm and -4.60.3mm in the controls....
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Papers by Luis Mezzomo