Pelagra
| Pelagra | |
|---|---|
 | |
| Osoba obolesa od pelagre sa ranama kože | |
| Specijalnost | Endokrinologija |
| Klasifikacija i eksterni resursi | |
| ICD-10 | E52 |
| ICD-9 | 265.2 |
| DiseasesDB | 9730 |
| MedlinePlus | 000342 |
| eMedicine | ped/1755 |
Pelagra je bolest vitaminske deficijencje, koja je najčešće uzrokovana hroničnim nedostatkom nijacina (vitamina B3) u ishrani. Ona može da bude uzrokava umanjenim unosim niacina ili triptofana,[1] kao i prekomernim unosim leucina.[2] Bolest takođe može da bude rezult promena proteinskog metabolizma usled poremećaja kao što je karcinoidni sindrom. Deficijencja aminokiseline lizina isto tako može da dovede do nedostatka niacina.[3]
Pelagra izaziva oštećenja nervnog sistema, zapaljenje kože, probavne smetnje i gubitak umnih sposobnosti
- ↑ Pitche P (2005). „Pellagra”. Sante 15 (3): 205–8. PMID 16207585.
- ↑ Bapurao S, Krishnaswamy K (1978). „Vitamin B6 nutritional status of pellagrins and their leucine tolerance”. Am J Clin Nutr 31 (5): 819–24. PMID 206127.
- ↑ „Lysine | amino acid health benefits, dietary sources, side effects”. Vitamins-supplements.org. Arhivirano iz originala na datum 2012-06-14. Pristupljeno 2012-07-31.
- Hampl JS, Hampl WS (1 November 1997). „Pellagra and the origin of a myth: evidence from European literature and folklore”. Journal of the Royal Society of Medicine 90 (11): 636–9. PMC 1296679. PMID 9496281.
- „Reports and Resolutions of the General Assembly of the State of South Carolina, Regular Session Commencing January 11, 1916”. Annual Report of the State Board of Health (1915-1916). (Columbia, S.C.: Gonzales and Bryan, state printers) 4. 1916.
- Beardsley E (2006). The Spartanburg Pellagra Hospital. In: The South Carolina Encyclopedia. Columbia, S.C: University of South Carolina Press. ISBN 1-57003-598-9.
- Swain CP, Tavill AS, Neale G (September 1976). „Studies of tryptophan and albumin metabolism in a patient with carcinoid syndrome, pellagra, and hypoproteinemia”. Gastroenterology 71 (3): 484–9. PMID 133045.
- Hendrick, Burton J. (April 1916). „The Mastery Of Pellagra: The Mysterious Disease, Almost Unknown In This Country Fifteen Years Ago, That Now Claims 7,500 Victims A Year And Is Spreading Rapidly”. The World's Work: A History of Our Time XXXI: 633–639. Pristupljeno 2009-08-04.
- Kraut, Alan. "Dr. Joseph Goldberger and the War on Pellagra, By Alan Kraut, Ph.D." Office of History, National Institutes of Health. Web. 03 Sept. 2010. <http://history.nih.gov/exhibits/goldberger/docs/pellegra_5.htm>.