Peptide identification via tandem mass spectrometry sequence database searching is a key
method in the array of tools available to the proteomics researcher. The ability to rapidly and …

Recent achievements in genomics have created an infrastructure of biological information.
The enormous success of genomics promptly induced a subsequent explosion in …

for processing and analyzing complex proteomics data sets in a platform-agnostic manner
has become critical. With version 3.0 of the ProteoWizard Toolkit8, we attempt to mitigate …

Skyline is a Windows client application for targeted proteomics method creation and
quantitative data analysis. It is open source and freely available for academic and …

Mass spectrometry is a highly complex analytical technique and mass spectrometry‐based
proteomics experiments can be subject to a large variability, which forms an obstacle to …

The completion of the Plasmodium falciparum clone 3D7 genome provides a basis on which
to conduct comparative proteomics studies of this human pathogen. Here, we applied a high …

The components of complex peptide mixtures can be separated by liquid chromatography,
fragmented by tandem mass spectrometry, and identified by the SEQUEST algorithm …

Extensive genomic characterization of human cancers presents the problem of inference
from genomic abnormalities to cancer phenotypes. To address this problem, we analysed …

Verification of candidate biomarkers relies upon specific, quantitative assays optimized for
selective detection of target proteins, and is increasingly viewed as a critical step in the …

To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …