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Competitive dynamics in cortical responses to visual stimuli

J Neurophysiol. 2005 Nov;94(5):3388-96. doi: 10.1152/jn.00159.2005. Epub 2005 Jun 8.

Abstract

Neurons in the visual cortex of the macaque monkey exhibit a variety of competitive behaviors, including normalization and oscillation, when presented with multiple visual stimuli. Here we argue that a biophysically plausible cortical circuit with opponent inhibition, spike-frequency adaptation, and synaptic depression can account for the full range of behaviors. The governing parameter is the strength of inhibition between competing neuronal pools. As the strength of inhibition is increased, the pattern of network behavior shifts from normalization mode to oscillatory mode, with oscillations occurring at progressively lower frequency until, at the extreme, winner-take-all behavior appears.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Action Potentials / physiology*
  • Animals
  • Biological Clocks / physiology*
  • Computer Simulation
  • Evoked Potentials, Visual / physiology*
  • Feedback
  • Macaca mulatta
  • Male
  • Models, Neurological*
  • Nerve Net / physiology
  • Neural Inhibition / physiology
  • Neurons, Afferent / physiology*
  • Photic Stimulation / methods
  • Task Performance and Analysis
  • Visual Cortex / physiology*
  • Visual Perception / physiology*