Abstract
Syntheses of higher acyclic nitrogen containing deoxy sugar derivatives via nitroaldol reaction of different nitroalkanes with 2,3-dideoxy-alpha,beta-unsaturated aldehydo sugars obtained from glycals namely acetylated glucal and galactal and their in vitro antimycobacterial activity are presented.
MeSH terms
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Acetylation
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Antitubercular Agents / chemical synthesis*
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Antitubercular Agents / chemistry
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Antitubercular Agents / pharmacology*
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Deoxy Sugars / chemistry*
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Deoxy Sugars / pharmacology*
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Hydrogenation
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Microbial Sensitivity Tests
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Molecular Structure
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Mycobacterium tuberculosis / drug effects
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Mycobacterium tuberculosis / growth & development
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Nitrogen / analysis*
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Structure-Activity Relationship
Substances
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Antitubercular Agents
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Deoxy Sugars
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Nitrogen