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ZA954692B - A process for the preparation and separation of diastereomeric salts of folinic acid - Google Patents

A process for the preparation and separation of diastereomeric salts of folinic acid

Info

Publication number
ZA954692B
ZA954692B ZA954692A ZA954692A ZA954692B ZA 954692 B ZA954692 B ZA 954692B ZA 954692 A ZA954692 A ZA 954692A ZA 954692 A ZA954692 A ZA 954692A ZA 954692 B ZA954692 B ZA 954692B
Authority
ZA
South Africa
Prior art keywords
separation
preparation
diastereomeric salts
folinic acid
salts
Prior art date
Application number
ZA954692A
Other languages
English (en)
Inventor
Ernst Felder
Giorgio Ripa
Carlo Distaso
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Publication of ZA954692B publication Critical patent/ZA954692B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
ZA954692A 1994-06-08 1995-06-07 A process for the preparation and separation of diastereomeric salts of folinic acid ZA954692B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI941193A IT1270185B (it) 1994-06-08 1994-06-08 Processo per l'ottenimento e la separazione dei sali diastereoisomeri dell'acido folinico

Publications (1)

Publication Number Publication Date
ZA954692B true ZA954692B (en) 1996-01-29

Family

ID=11369074

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA954692A ZA954692B (en) 1994-06-08 1995-06-07 A process for the preparation and separation of diastereomeric salts of folinic acid

Country Status (12)

Country Link
EP (1) EP0755397B1 (it)
JP (1) JP4241925B2 (it)
KR (1) KR100262684B1 (it)
AT (1) ATE169918T1 (it)
AU (1) AU2672695A (it)
DE (2) DE755397T1 (it)
ES (1) ES2101665T1 (it)
GR (1) GR970300023T1 (it)
IL (1) IL114050A0 (it)
IT (1) IT1270185B (it)
WO (1) WO1995033749A1 (it)
ZA (1) ZA954692B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013025203A1 (en) * 2011-08-16 2013-02-21 Watson Laboratories, Inc. Resolution of tetrahydrofolic acid derivatives
CN103102350A (zh) * 2011-11-11 2013-05-15 重庆华邦胜凯制药有限公司 一种左亚叶酸盐的制备方法
CN113666931B (zh) * 2021-09-07 2023-11-03 浙江大为药业有限公司 一种高纯左亚叶酸钙的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH680731A5 (it) * 1990-04-12 1992-10-30 Sapec Fine Chemicals
DE4136921A1 (de) * 1991-11-11 1993-05-13 Knoll Ag Verfahren zur trennung von 5-methyl-tetrahydrofolsaeure
IT1254635B (it) * 1992-02-20 1995-09-28 Bracco Spa Processo per la separazione degli stereoisomeri dell'acido folinico

Also Published As

Publication number Publication date
EP0755397B1 (en) 1998-08-19
ATE169918T1 (de) 1998-09-15
WO1995033749A1 (en) 1995-12-14
GR970300023T1 (en) 1997-08-29
ITMI941193A0 (it) 1994-06-08
EP0755397A1 (en) 1997-01-29
AU2672695A (en) 1996-01-04
JPH10500972A (ja) 1998-01-27
DE755397T1 (de) 1997-09-25
KR100262684B1 (ko) 2000-08-01
JP4241925B2 (ja) 2009-03-18
DE69504189D1 (de) 1998-09-24
ITMI941193A1 (it) 1995-12-08
IT1270185B (it) 1997-04-29
ES2101665T1 (es) 1997-07-16
KR970703343A (ko) 1997-07-03
IL114050A0 (en) 1995-10-31
DE69504189T2 (de) 1998-12-24

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