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ZA947710B - Imidazol-4 ylpiperdine derivatives, their preparation and their application in therapeutics. - Google Patents

Imidazol-4 ylpiperdine derivatives, their preparation and their application in therapeutics.

Info

Publication number
ZA947710B
ZA947710B ZA947710A ZA947710A ZA947710B ZA 947710 B ZA947710 B ZA 947710B ZA 947710 A ZA947710 A ZA 947710A ZA 947710 A ZA947710 A ZA 947710A ZA 947710 B ZA947710 B ZA 947710B
Authority
ZA
South Africa
Prior art keywords
ylpiperdine
imidazol
therapeutics
derivatives
preparation
Prior art date
Application number
ZA947710A
Other languages
English (en)
Inventor
Samir Jegham
Gerard Defosse
Thomas Andrew Purcell
Luc Even
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA947710B publication Critical patent/ZA947710B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA947710A 1993-10-04 1994-10-03 Imidazol-4 ylpiperdine derivatives, their preparation and their application in therapeutics. ZA947710B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9311771A FR2710915B1 (fr) 1993-10-04 1993-10-04 Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number Publication Date
ZA947710B true ZA947710B (en) 1995-08-10

Family

ID=9451496

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA947710A ZA947710B (en) 1993-10-04 1994-10-03 Imidazol-4 ylpiperdine derivatives, their preparation and their application in therapeutics.

Country Status (18)

Country Link
US (1) US5589476A (xx)
EP (1) EP0646583A1 (xx)
JP (1) JPH07179466A (xx)
KR (1) KR950011435A (xx)
CN (1) CN1109471A (xx)
AU (1) AU7432994A (xx)
CA (1) CA2133491A1 (xx)
CZ (1) CZ241994A3 (xx)
FI (1) FI944600A (xx)
FR (1) FR2710915B1 (xx)
HU (1) HUT71120A (xx)
IL (1) IL111148A0 (xx)
NO (1) NO943682L (xx)
NZ (1) NZ264596A (xx)
PL (1) PL305288A1 (xx)
RU (1) RU94036003A (xx)
SK (1) SK119494A3 (xx)
ZA (1) ZA947710B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5500423A (en) * 1994-09-09 1996-03-19 Hoechst-Roussel Pharmaceuticals Inc. 5,6-dihydro-4H-imidazo[4,5,1-ij]quinolines
FR2731708B1 (fr) * 1995-03-13 1997-04-30 Synthelabo Derives de piperidine, leur procede de preparation et leur application en therapeutique
KR19990045728A (ko) * 1995-09-18 1999-06-25 그레이엄 브레레톤, 레슬리 에드워즈 운동이상증에 대한 ５-ｈｔ３ 수용체 길항제
FR2747678B1 (fr) * 1996-04-22 1998-05-22 Synthelabo Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique
FR2753196B1 (fr) * 1996-09-12 1998-10-23 Synthelabo Derives d'indazole tricyclique, leur preparation et leur application en therapeutique
ID28510A (id) * 1998-08-21 2001-05-31 Novartis Ag Formulasi oral yang baru untuk agonis atau antagonis 5-ht4
IT1303123B1 (it) 1998-10-13 2000-10-30 Rotta Research Lab Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
GB9918425D0 (en) * 1999-08-04 1999-10-06 Novartis Ag Organic compounds
FR2812878B1 (fr) * 2000-08-08 2002-10-11 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816619B1 (fr) * 2000-11-15 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
CA2412368A1 (fr) * 2000-08-08 2002-02-14 Sanofi-Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816941B1 (fr) * 2000-11-23 2003-01-31 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
FR2816942B1 (fr) * 2000-11-23 2003-05-09 Sanofi Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
US20040242635A1 (en) * 2001-03-30 2004-12-02 Painter Rachel J. Encapsulated dyes in cosmetic compositions
AU2003240742A1 (en) * 2002-06-07 2003-12-22 Altana Pharma Ag 4,5-dihydro-imidazo (4,5,1-ij) quinolin-6-ones derivatives and their use as poly (adp-ribosyl) transferase (parp) inhibitors
AR095326A1 (es) 2013-03-15 2015-10-07 Incyte Corp Heterociclos tricíclicos como inhibidores de la proteína bet
CA2917319A1 (en) 2013-07-08 2015-01-15 Incyte Holdings Corporation Tricyclic heterocycles as bet protein inhibitors
US9399640B2 (en) 2013-11-26 2016-07-26 Incyte Corporation Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
US9315501B2 (en) 2013-11-26 2016-04-19 Incyte Corporation Bicyclic heterocycles as BET protein inhibitors
WO2015095492A1 (en) 2013-12-19 2015-06-25 Incyte Corporation Tricyclic heterocycles as bet protein inhibitors
AU2015249810B2 (en) 2014-04-23 2019-04-18 Incyte Holdings Corporation 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins
JP6599979B2 (ja) 2014-09-15 2019-10-30 インサイト・コーポレイション Ｂｅｔタンパク質阻害剤として用いるための三環式複素環化合物
WO2017075377A1 (en) 2015-10-29 2017-05-04 Incyte Corporation Amorphous solid form of a bet protein inhibitor
KR102643344B1 (ko) 2016-06-20 2024-03-07 인사이트 코포레이션 Bet 저해제의 결정질 고체 형태
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939138A (en) * 1988-12-29 1990-07-03 Sterling Drug Inc. 2- and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo(1,2,3-DE)-1,4-benzoxazines
FR2674855B1 (fr) * 1991-04-03 1994-01-14 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
SK119494A3 (en) 1995-05-10
JPH07179466A (ja) 1995-07-18
EP0646583A1 (fr) 1995-04-05
RU94036003A (ru) 1996-08-10
CN1109471A (zh) 1995-10-04
FR2710915A1 (fr) 1995-04-14
CZ241994A3 (en) 1995-04-12
PL305288A1 (en) 1995-04-18
FR2710915B1 (fr) 1995-11-24
IL111148A0 (en) 1994-12-29
NZ264596A (en) 1995-11-27
AU7432994A (en) 1995-04-13
HUT71120A (en) 1995-11-28
KR950011435A (ko) 1995-05-15
CA2133491A1 (en) 1995-04-05
US5589476A (en) 1996-12-31
HU9402832D0 (en) 1995-01-30
NO943682L (no) 1995-04-05
FI944600A (fi) 1995-04-05
FI944600A0 (fi) 1994-10-03
NO943682D0 (no) 1994-10-03

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