ZA916902B - Hetrazepinoid amide derivatives - Google Patents

Hetrazepinoid amide derivatives

Info

Publication number: ZA916902B
Authority: ZA; South Africa
Prior art keywords: hetrazepinoid; amide derivatives; amide; derivatives; hetrazepinoid amide
Prior art date: 1990-08-30

Application number

ZA916902A

Other languages

English (en)

Inventor

Karl-Heinz Weber

Weber Karl-Heinz

Werner Stransky

Stransky Werner

Ulrike Kuefner-Muehl

Kuefner-Muehl Ulrike

Hubert Heuer

Heuer Hubert

Franz Birke

Birke Franz

Wolf-Dietrich Bechtel

Bechtel Wolf-Dietrich

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-30

Filing date

1991-08-30

Publication date

1992-04-29

1991-08-30 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

1992-04-29 Publication of ZA916902B publication Critical patent/ZA916902B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ZA916902A 1990-08-30 1991-08-30 Hetrazepinoid amide derivatives ZA916902B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4027470A DE4027470A1 (de)	1990-08-30	1990-08-30	Neue hetrazepinoide amide

Publications (1)

Publication Number	Publication Date
ZA916902B true ZA916902B (en)	1992-04-29

Family

ID=6413254

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA916902A ZA916902B (en)	1990-08-30	1991-08-30	Hetrazepinoid amide derivatives

Country Status (17)

Country	Link
US (1)	US5698552A (xx)
EP (1)	EP0475204A3 (xx)
JP (1)	JPH04261181A (xx)
KR (1)	KR920004394A (xx)
AU (1)	AU8346291A (xx)
CA (1)	CA2050268A1 (xx)
CS (1)	CS265391A3 (xx)
DE (1)	DE4027470A1 (xx)
FI (1)	FI914071A (xx)
HU (1)	HU912821D0 (xx)
IE (1)	IE913043A1 (xx)
IL (1)	IL99325A0 (xx)
MX (1)	MX9100845A (xx)
NO (1)	NO913391L (xx)
PL (1)	PL291562A1 (xx)
PT (1)	PT98816B (xx)
ZA (1)	ZA916902B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994004537A2 (en) *	1992-08-20	1994-03-03	Cytomed, Inc.	Dual functional anti-inflammatory and immunosuppressive agents
US5821924A (en) *	1992-09-04	1998-10-13	Elonex I.P. Holdings, Ltd.	Computer peripherals low-power-consumption standby system
US5389952A (en) *	1992-12-02	1995-02-14	Cordata Inc.	Low-power-consumption monitor standby system
US5302590A (en) *	1992-12-18	1994-04-12	Hoffmann-La Roche Inc.	Compounds useful as dual antagonists of platelet activating factor and leukotriene D4
PT989131E (pt) *	1996-09-13	2003-03-31	Mitsubishi Pharma Corp	Compostos de trienotriazolodiazepina e suas utilizacoes com fins medicinais
AR084070A1 (es)	2010-12-02	2013-04-17	Constellation Pharmaceuticals Inc	Inhibidores del bromodominio y usos de los mismos
US9249161B2 (en)	2010-12-02	2016-02-02	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
EP2705039B1 (en)	2011-05-04	2017-07-26	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
EP2721031B1 (en)	2011-06-17	2016-01-20	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
TWI602820B (zh)	2012-06-06	2017-10-21	星宿藥物公司	溴域抑制劑及其用途
US9624244B2 (en)	2012-06-06	2017-04-18	Constellation Pharmaceuticals, Inc.	Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof
PT3157928T (pt)	2014-06-20	2019-05-30	Constellation Pharmaceuticals Inc	Formas cristalinas de 2-((4s)-6-(4-clorofenil)-1-metil-4h-benzo[c] isoxazolo[4,5-e]azepin-4-il)acetamida

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3435973A1 (de) *	1984-10-01	1986-04-10	Boehringer Ingelheim KG, 6507 Ingelheim	Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) *	1985-01-25	1986-07-31	Boehringer Ingelheim KG, 6507 Ingelheim	Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3778559D1 (de) *	1986-01-21	1992-06-04	Boehringer Ingelheim Kg	Thieno-1,4-diazepine.
PH30676A (en) *	1986-07-22	1997-09-16	Boehringer Ingelhein Kg	Hetrazepine compounds which have useful pharmaceutical utility
CA1324863C (en) *	1988-01-30	1993-11-30	Minoru Moriwaki	Thienotriazolodiazepine compounds and pharmaceutical uses thereof
FI95708C (fi) *	1988-10-31	1996-03-11	Eisai Co Ltd	Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
EP0368175A1 (de) *	1988-11-06	1990-05-16	Boehringer Ingelheim Kg	3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin.
DE3909012A1 (de) *	1989-03-18	1990-09-20	Boehringer Ingelheim Kg	Verbessertes verfahren zur herstellung von enantiomerenreinen hetrazepinen
GB8907256D0 (en) *	1989-03-31	1989-05-17	Rech Et D Applic Scient Scras	New derivatives of hetrazepine as anti-asthmatic anti-allergic and gastro-intestinal protectors
CA2020806A1 (en) *	1989-07-12	1991-01-13	Karl-Heinz Weber	Thienodiazepine derivatives
DE4010528A1 (de) *	1990-04-02	1991-10-17	Boehringer Ingelheim Kg	Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine

1990
- 1990-08-30 DE DE4027470A patent/DE4027470A1/de not_active Withdrawn
1991
- 1991-08-28 MX MX9100845A patent/MX9100845A/es unknown
- 1991-08-28 CS CS912653A patent/CS265391A3/cs unknown
- 1991-08-28 IL IL99325A patent/IL99325A0/xx unknown
- 1991-08-29 PL PL29156291A patent/PL291562A1/xx unknown
- 1991-08-29 EP EP19910114518 patent/EP0475204A3/de not_active Withdrawn
- 1991-08-29 JP JP3218916A patent/JPH04261181A/ja active Pending
- 1991-08-29 HU HU912821A patent/HU912821D0/hu unknown
- 1991-08-29 FI FI914071A patent/FI914071A/fi not_active Application Discontinuation
- 1991-08-29 PT PT98816A patent/PT98816B/pt active IP Right Grant
- 1991-08-29 CA CA002050268A patent/CA2050268A1/en not_active Abandoned
- 1991-08-29 NO NO91913391A patent/NO913391L/no unknown
- 1991-08-29 IE IE304391A patent/IE913043A1/en unknown
- 1991-08-30 KR KR1019910015086A patent/KR920004394A/ko not_active Application Discontinuation
- 1991-08-30 AU AU83462/91A patent/AU8346291A/en not_active Abandoned
- 1991-08-30 ZA ZA916902A patent/ZA916902B/xx unknown
1995
- 1995-05-31 US US08/453,038 patent/US5698552A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FI914071A0 (fi)	1991-08-29
US5698552A (en)	1997-12-16
PL291562A1 (en)	1992-10-05
DE4027470A1 (de)	1992-03-05
AU8346291A (en)	1992-03-05
PT98816B (pt)	1999-01-29
IE913043A1 (en)	1992-03-11
PT98816A (pt)	1992-07-31
CA2050268A1 (en)	1992-03-01
FI914071A (fi)	1992-03-01
HUT62007A (en)	1993-03-29
EP0475204A3 (en)	1992-05-13
HU912821D0 (en)	1993-03-29
CS265391A3 (en)	1992-03-18
JPH04261181A (ja)	1992-09-17
MX9100845A (es)	1992-04-01
KR920004394A (ko)	1992-03-27
IL99325A0 (en)	1992-07-15
EP0475204A2 (de)	1992-03-18
NO913391L (no)	1992-03-02
NO913391D0 (no)	1991-08-29

Publication	Publication Date	Title
EP0440950A3 (en)	1992-02-12	Halogenallyl-azolyl derivatives
HU912356D0 (en)	1991-12-30	Rapacmycine derivatives
EP0470466A3 (en)	1992-07-29	Halogenalkyl-azolyl derivatives
ZA914484B (en)	1992-03-25	Azolyl-propanol derivatives
IL96819A0 (en)	1991-09-16	Azaoxindole derivatives
LTIP848A (en)	1995-02-27	Hiv-inhibiting benzene-acetamide derivatives
IL99576A0 (en)	1992-08-18	Triazacyclohexane derivatives
EP0485984A3 (en)	1993-01-20	Diarylmethoxypiperidine derivatives
ZA916902B (en)	1992-04-29	Hetrazepinoid amide derivatives
HU9500330D0 (en)	1995-03-28	Amide derivatives
OA09670A (en)	1993-05-15	Carbo-nucleoside derivatives
EP0440949A3 (en)	1992-02-12	Halogenallyl-azolyl derivatives
ZA914675B (en)	1992-04-29	5-isothiazolamine derivatives
IL98897A0 (en)	1992-07-15	Carboxymethylcyclopropane derivatives
GB9004501D0 (en)	1990-04-25	Amide derivatives
GB2249094B (en)	1994-05-11	Hetero-imidazodiazepine derivatives
GB9006772D0 (en)	1990-05-23	4-piperidinyl-ergoline derivatives
GB2305171B (en)	1997-08-13	Amide derivatives
GB9120228D0 (en)	1991-11-06	Amide derivatives
GB9101665D0 (en)	1991-03-06	Amide derivatives
EG19474A (en)	1995-06-29	Nitroenamine derivatives
EG19362A (en)	1994-12-30	Azoaxindole derivatives
ZA935543B (en)	1995-01-30	Amide derivatives
GB9611338D0 (en)	1996-08-07	Amide derivatives
AU5992790A (en)	1992-01-30	Amide derivatives