ZA875043B - 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments - Google Patents

7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments

Info

Publication number: ZA875043B
Authority: ZA; South Africa
Prior art keywords: aminoacyloxypolyoxylabdanes; acyloxy; medicaments; preparation
Prior art date: 1986-07-11

Application number

ZA875043A

Inventor

Yatendra Khandelwal

Khandelwal Yatendra

Ramanujam Rajgopalan

Rajgopalan Ramanujam

Alihussein Nomanbha Dohadwalla

Nomanbhai Dohadwall Alihussein

Richard Helmut Rupp

Helmut Rupp Richard

Noel John De Souza

John De Souza Noel

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-11

Filing date

1987-07-10

Publication date

1988-03-30

1987-07-10 Application filed by Hoechst Ag filed Critical Hoechst Ag

1988-03-30 Publication of ZA875043B publication Critical patent/ZA875043B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)

ZA875043A 1986-07-11 1987-07-10 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments ZA875043B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19863623300 DE3623300A1 (en)	1986-07-11	1986-07-11	7-ACYLOXY-6-AMINOACYLOXYPOLYOXYLABDANE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT

Publications (1)

Publication Number	Publication Date
ZA875043B true ZA875043B (en)	1988-03-30

Family

ID=6304882

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA875043A ZA875043B (en)	1986-07-11	1987-07-10	7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments

Country Status (10)

Country	Link
EP (1)	EP0252482A3 (en)
JP (1)	JPS6323878A (en)
KR (1)	KR880001642A (en)
AU (1)	AU7553887A (en)
DE (1)	DE3623300A1 (en)
DK (1)	DK354687A (en)
HU (1)	HU203229B (en)
IL (1)	IL83152A0 (en)
PT (1)	PT85302B (en)
ZA (1)	ZA875043B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4963537A (en) *	1985-03-01	1990-10-16	Hoechst-Roussel Pharmaceuticals Inc.	Labdane compounds, pharmaceutical compositions and use
US4851397A (en) *	1985-03-01	1989-07-25	Hoechst-Roussel Pharmaceuticals Inc.	Labdanes, pharmaceutical compositions, and their use
AU591196B2 (en) *	1985-11-15	1989-11-30	Nippon Kayaku Kabushiki Kaisha	Novel forskolin derivatives
JPS6310783A (en) *	1985-11-15	1988-01-18	Nippon Kayaku Co Ltd	Novel forskolin derivative
CA1307530C (en) *	1986-12-29	1992-09-15	Hoechst-Roussel Pharmaceuticals Inc.	Carbamoyloxylabdanes, intermediates and a process for the preparation thereof and their use as medicaments
US5646175A (en) *	1987-12-28	1997-07-08	Hoechst Marion Roussel, Inc.	Carbamoyloxylabdane compounds
US4920146A (en) *	1986-12-29	1990-04-24	Hoechst Roussel Pharmaceuticals Inc.	Carbamoyloxylabdane compounds useful in reducing intraocular pressure
IN166900B (en) *	1987-06-03	1990-08-04	Hoechst India
JP2504934B2 (en) *	1987-06-29	1996-06-05	日本化薬株式会社	1,6,7-Triacylforskolin derivative
JPH0684367B2 (en) *	1987-06-29	1994-10-26	日本化薬株式会社	New method for producing forskolin derivative
DE3737353A1 (en) *	1987-11-04	1989-05-18	Hoechst Ag	NEW ACYLLABDANE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
US4883793A (en) *	1988-05-09	1989-11-28	Hoechst-Roussel Pharmaceuticals Inc.	Hydrazinocarbonyloxylabdanes for treating cardiac failure
EP0447962A1 (en) *	1990-03-17	1991-09-25	Hoechst Aktiengesellschaft	Labdanes and process for their preparation
US5869523A (en) *	1990-07-24	1999-02-09	Hoechst Aktiengesellschaft	Process for the preparation of 6-(substitutedaminopropionyl)-derivatives of forskolin
JP3557095B2 (en) *	1998-04-20	2004-08-25	高砂香料工業株式会社	Melanin production inhibitor
WO2016054237A2 (en)	2014-10-03	2016-04-07	Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center	Poly (adp-ribose) polymerase 1 inhibitors structurally unrelated to nad

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1985003637A1 (en) *	1984-02-24	1985-08-29	Halprin Kenneth M	Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin
IN163242B (en) *	1985-05-03	1988-08-27	Hoechst India
AU591196B2 (en) *	1985-11-15	1989-11-30	Nippon Kayaku Kabushiki Kaisha	Novel forskolin derivatives

1986
- 1986-07-11 DE DE19863623300 patent/DE3623300A1/en not_active Withdrawn
1987
- 1987-07-07 EP EP87109750A patent/EP0252482A3/en not_active Withdrawn
- 1987-07-09 KR KR1019870007339A patent/KR880001642A/en not_active Application Discontinuation
- 1987-07-09 DK DK354687A patent/DK354687A/en not_active Application Discontinuation
- 1987-07-10 HU HU873173A patent/HU203229B/en not_active IP Right Cessation
- 1987-07-10 PT PT85302A patent/PT85302B/en not_active IP Right Cessation
- 1987-07-10 IL IL83152A patent/IL83152A0/en unknown
- 1987-07-10 JP JP62171325A patent/JPS6323878A/en active Pending
- 1987-07-10 ZA ZA875043A patent/ZA875043B/en unknown
- 1987-07-10 AU AU75538/87A patent/AU7553887A/en not_active Abandoned

Also Published As

Publication number	Publication date
HU203229B (en)	1991-06-28
AU7553887A (en)	1988-01-14
DE3623300A1 (en)	1988-01-21
DK354687A (en)	1988-01-12
DK354687D0 (en)	1987-07-09
JPS6323878A (en)	1988-02-01
KR880001642A (en)	1988-04-25
HUT46900A (en)	1988-12-28
PT85302B (en)	1990-03-30
PT85302A (en)	1987-08-01
IL83152A0 (en)	1987-12-31
EP0252482A3 (en)	1988-05-04
EP0252482A2 (en)	1988-01-13

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